A5475

ALX-1393

>98% (HPLC), powder

• Synonym(e): O-[(2-Benzyloxyphenyl-3-flurophenyl)methyl]-L-serine
• Empirische Formel (Hill-System): C₂₃H₂₂NO₄F
• Molekulargewicht: 395.42
• MDL-Nummer: MFCD04974486
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724393

Eigenschaften

• Assay: >98% (HPLC)
• Form: powder
• Farbe: white
• Löslichkeit: DMSO: soluble ~20 mg/mL
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• SMILES String: N[C@@H](COC(c1cccc(F)c1)c2ccccc2OCc3ccccc3)C(O)=O
• InChI: 1S/C23H22FNO4/c24-18-10-6-9-17(13-18)22(29-15-20(25)23(26)27)19-11-4-5-12-21(19)28-14-16-7-2-1-3-8-16/h1-13,20,22H,14-15,25H2,(H,26,27)/t20-,22?/m0/s1
• InChIKey: ADUSZEGHFWRTQS-AIBWNMTMSA-N

Beschreibung

Anwendung

ALX-1393 is a GlyT-2 glycine transporter inhibitor and GlyT2 may be a novel therapeutic target for the treatment of overactive bladder and/or bladder hypersensitive disorders such as bladder pain syndrome/interstitial cystitis.

Biochem./physiol. Wirkung

GlyT-2 glycine transporter inhibitor.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)