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76904

Sigma-Aldrich

Vecuroniumbromid

Synonym(e):

1-[(2β,3α,5α,16β,17β)-3,17-Bis-(acetyloxy)-2-(1-piperidinyl)-androstan-16-yl]-1-methyl-piperidiniumbromid

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About This Item

Empirische Formel (Hill-System):
C34H57BrN2O4
CAS-Nummer:
50700-72-6
Molekulargewicht:
637.73
Beilstein:
4837308
EG-Nummer:
256-723-9
MDL-Nummer:
MFCD00867762
UNSPSC-Code:
51152000
PubChem Substanz-ID:
329767429
NACRES:
NA.77

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Biologische Quelle

synthetic

Qualitätsniveau

100

Assay

≥97.0% (TLC)

Form

powder or crystals

Funktionelle Gruppe

carboxylic acid

SMILES String

[Br-].CC(=O)O[C@H]1C[C@@H]2CC[C@@H]3[C@H](CC[C@@]4(C)[C@H]3C[C@@H]([C@@H]4OC(C)=O)[N+]5(C)CCCCC5)[C@@]2(C)C[C@@H]1N6CCCCC6

InChI

1S/C34H57N2O4.BrH/c1-23(37)39-31-20-25-12-13-26-27(34(25,4)22-29(31)35-16-8-6-9-17-35)14-15-33(3)28(26)21-30(32(33)40-24(2)38)36(5)18-10-7-11-19-36;/h25-32H,6-22H2,1-5H3;1H/q+1;/p-1/t25-,26+,27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1

InChIKey

VEPSYABRBFXYIB-PWXDFCLTSA-M

Angaben zum Gen

human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

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Verwandte Kategorien

Biochem./physiol. Wirkung

Vecuronium Bromide is an aminosteroidal neuromuscular blocking agent. It relaxes the skeletal muscle and decreases oxygen consumption during surgery. It competes with acetylcholine and bind to cholinergic receptors at neuromuscular junctions.[1][2]

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
BCCK9926
BCCJ5183
BCCF6335
BCCB3328
BCBW4131

Die passende Version wird nicht angezeigt?

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Kaliumphosphat for molecular biology, ≥98.0%

Sigma-Aldrich

P9791

Kaliumphosphat

Hong WANG et al.
Acta pharmacologica Sinica, 31(12), 1541-1546 (2010-11-26)
to investigate the changing resistance to nondepolarizing muscle relaxants (NDMRs) during the first month after denervation. the denervated and innervated skeletal muscle cells were examined on days 1, 4, 7, 14, 21, and 28 after denervation. Individual denervated and innervated
Hong Wang et al.
Acta pharmacologica Sinica, 32(12), 1454-1459 (2011-10-12)
To investigate the effect of magnesium sulfate and its interaction with the non-depolarizing muscle relaxant vecuronium at adult muscle-type acetylcholine receptors in vitro. Adult muscle-type acetylcholine receptors were expressed in HEK293 cells. Drug-containing solution was applied via a gravity-driven perfusion
Shawn P Vorce et al.
Journal of analytical toxicology, 32(6), 422-427 (2008-07-26)
The apparent recreational use of an aminosteroidal non-depolarizing neuromuscular blocking agent, vecuronium, is reported in this postmortem investigation. A quantitative method for the analysis of vecuronium and its active metabolite, 3-desacetylvecuronium, in blood and tissue samples was developed using liquid
K Nitahara et al.
Anaesthesia, 68(9), 904-907 (2013-06-25)
We investigated whether a bolus injection of 20 ml saline with arm elevation might shorten the onset time of vecuronium administered via a dorsal hand vein. Thirty patients were randomly allocated to the bolus saline group or control group. General
L Liu et al.
British journal of anaesthesia, 112(1), 159-168 (2013-08-02)
Resistance to non-depolarizing neuromuscular blocking agents induced by sepsis is associated with the qualitative change in the nicotinic acetylcholine receptor (nAChR). This study aims to investigate the effects of sepsis on the neuromuscular block properties of vecuronium in relation to
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Questions

  1. Please let us know the next retest/Expiry date if it is not mentioned in the COA or bottle given for Vecuronium Bromide, Product Number 76904, Batch Number BCCJ5183, thanks. Or please guide, how to check the same

    1 answer

    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment.

      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

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