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Merck

449R-1

Sigma-Aldrich

S100 beta (EP32) Rabbit Monoclonal Primary Antibody

Synonym(e):

S100 Calcium Binding Protein B

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

EP32, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (449R-14)
vial of 0.1 mL concentrate Research Use Only (449R-14-RUO)
vial of 0.5 mL concentrate (449R-15)
vial of 1.0 mL concentrate (449R-16)
vial of 1.0 mL concentrate Research Use Only (449R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (449R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (449R-17)
vial of 7.0 mL pre-dilute ready-to-use (449R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (449R-18-RUO)

Hersteller/Markenname

Cell Marque

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500 (concentrated)

Isotyp

IgG

Kontrolle

melanoma

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Allgemeine Beschreibung

S100 calcium binding protein B (S100 beta) is a member of the multifunctional S100 family of proteins. S100 beta acts as a stimulator of proliferation and migration and as an inhibitor of apoptosis and differentiation in many cell types including astrocytes, Schwann cells, chondrocytes, adipocytes, certain neuronal populations, melanocytes, Langerhans cells, histiocytes, epithelial, and myoepithelial cells. S100 beta is also expressed in neoplasms derived from these cell types, making it a useful marker for the identification of melanoma and various nervous system tumors. Although ubiquitous, S100 beta has proven to be a sensitive marker for malignant melanoma, including desmoplastic and metastatic variants.

Qualität


IVD

IVD

IVD

RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

R Donato et al.
Current molecular medicine, 13(1), 24-57 (2012-07-28)
The S100 protein family consists of 24 members functionally distributed into three main subgroups: those that only exert intracellular regulatory effects, those with intracellular and extracellular functions and those which mainly exert extracellular regulatory effects. S100 proteins are only expressed
F Sedaghat et al.
Hippokratia, 12(4), 198-204 (2009-01-23)
The members of the S100 protein family are multifunctional proteins with a regulatory role in a variety of cellular processes. They exert their actions usually through calcium binding, although Zn2+ and Cu2+ have also been shown to regulate their biological
Markku Miettinen et al.
The American journal of surgical pathology, 38(3), 410-420 (2014-02-15)
The SALL4 transcription factor is associated with embryonic cell pluripotency and has been shown as a useful immunohistochemical marker for germ cell tumors. However, information of SALL4 distribution in normal human tissues and non-germ cell tumors is limited. In this
C deBlacam et al.
British journal of cancer, 105(1), 118-123 (2011-06-10)
Cutaneous melanoma is an aggressive disease. S100beta is an established biomarker of disease progression; however, the mechanism of its regulation in melanoma is undefined. Expression of HOXC11 and SRC-1 was examined by immunohistochemistry and immunofluorescence. Molecular and cellular techniques were

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