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Y0000108

Trihexyphenidyl -hydrochlorid

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(±)-α-Cyclohexyl-α-phenyl-1-piperidinpropanol -hydrochlorid

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About This Item

Empirische Formel (Hill-System):
C20H31NO · HCl
CAS-Nummer:
52-49-3
Molekulargewicht:
337.93
MDL-Nummer:
MFCD00058212
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329830848
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

trihexyphenidyl hydrochloride

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

Cl.OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3

InChI

1S/C20H31NO.ClH/c22-20(18-10-4-1-5-11-18,19-12-6-2-7-13-19)14-17-21-15-8-3-9-16-21;/h1,4-5,10-11,19,22H,2-3,6-9,12-17H2;1H

InChIKey

QDWJJTJNXAKQKD-UHFFFAOYSA-N

Angaben zum Gen

human ... CHRM1(1128)

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Trihexyphenidyl hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

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Analysenzertifikate (COA)

Lot/Batch Number

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[Case report: a case of anterocollis ameliorated by trihexyphenidyl].
Ayako Shioya et al.
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 100(11), 3325-3328 (2012-01-19)
Bradley James Robottom et al.
The neurologist, 17(6), 340-341 (2011-11-03)
Trihexyphenidyl is 1 of the most effective agents for treatment of young-onset dystonia. As such, women of childbearing potential use trihexyphenidyl despite inadequate information about potential effects on pregnancy, labor, and fetal development. We report 2 uncomplicated pregnancies in 1
Alex Pollock et al.
The Cochrane database of systematic reviews, (10)(10), CD008389-CD008389 (2011-10-07)
Eye movement disorders may affect over 70% of stroke patients. These eye movement disorders can result in difficulty maintaining the normal ocular position and difficulty moving the eyes appropriately. The resulting functional disabilities include a loss of depth perception, reduced
Clinical reasoning: A 13-year-old boy presenting with dystonia, myoclonus, and anxiety.
Joanna S Blackburn et al.
Neurology, 78(11), e72-e76 (2012-03-14)
Yasumasa Yoshiyama et al.
Neurobiology of disease, 45(1), 329-336 (2011-09-06)
Anticholinergics, and drugs with anticholinergic properties, are widely and frequently prescribed, especially to the elderly. It is well known that these drugs decrease cognitive function and increase the risk of dementia. Although the mechanism of anticholinergic drug-induced cognitive impairment has
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