PHR1763

Cefepime hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Cefepime hydrochloride, Cefepime dihydrochloride monohydrate
• Lineare Formel: C₁₉H₂₅N₆O₅S₂Cl · HCl · H₂O
• CAS-Nummer: 123171-59-5
• Molekulargewicht: 571.50
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. Y0000633; traceable to USP 1097636
• API-Familie: cefepime
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [s]1[c]([nH]c(c1)\C(=N\OC)\C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(=O)[O-])C[N+]4(CCCC4)C)=N.Cl.Cl.O
• InChI: 1S/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1
• InChIKey: LRAJHPGSGBRUJN-OMIVUECESA-N

Beschreibung

Allgemeine Beschreibung

Cefepime hydrochloride is one of the fourth-generation, semisynthetic, broad-spectrum, cephalosporin β-lactam antibiotic drugs administered parenterally in patients with moderate-to-severe infections like pneumonia, uncomplicated urinary tract infections, skin and soft tissue infections, etc. Its mode of action involves the penetration of outer cell wall of gram negative bacteria.[1]
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Anwendung

Cefepime hydrochloride has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry[2] and chromatography[3][1][4] techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB8503 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable