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Merck

PHL80356

Astilbin

phyproof® Reference Substance

Synonym(e):

Taxifolin-3-rhamnosid

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About This Item

Empirische Formel (Hill-System):
C21H22O11
CAS-Nummer:
Molekulargewicht:
450.39
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

primary reference standard

Produktlinie

phyproof® Reference Substance

Assay

≥95.0% (HPLC)

Hersteller/Markenname

PhytoLab

Format

neat

Lagertemp.

2-8°C

SMILES String

O=C1C2=C(O)C=C(O)C=C2O[C@H](C3=CC(O)=C(O)C=C3)[C@H]1O[C@@]4([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O4

InChI

1S/C21H22O11/c1-7-15(26)17(28)18(29)21(30-7)32-20-16(27)14-12(25)5-9(22)6-13(14)31-19(20)8-2-3-10(23)11(24)4-8/h2-7,15,17-26,28-29H,1H3/t7-,15-,17+,18+,19-,20+,21-/m0/s1

InChIKey

ZROGCCBNZBKLEL-MFSALPCASA-N

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Verwandte Kategorien

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem./physiol. Wirkung

Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations. Immunosuppresive. Antiproliferative.

Rechtliche Hinweise

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Yu Li et al.
International immunopharmacology, 84, 106571-106571 (2020-05-16)
Ischaemic stroke is a lethal cerebrovascular disease that occurs worldwide. Astilbin is a natural flavonoid compound with various physiological activities. The purpose of this study was to investigate the neuroprotective effects of Astilbin after cerebral ischaemia reperfusion (I/R) injury. The
Dan Zheng et al.
Molecules (Basel, Switzerland), 25(20) (2020-10-21)
Astilbin and neoastilbin are two flavonoid stereoisomers. In the present study, their solubility, stability, and bioavailability were compared in a rat. The results revealed that the water solubility of astilbin and neoastilbin was 132.72 μg/mL and 217.16 μg/mL, respectively. The
Meiyun Shi et al.
The Journal of pharmacy and pharmacology, 72(8), 1061-1071 (2020-04-30)
The purpose of this study is to reveal the pharmacokinetic profiles of astilbin with various doses in rats and investigate the oral absolute bioavailability and tissue distribution of astilbin after oral administration. Wistar rats were orally administered astilbin 12, 24 mg/kg
Qianni Duan et al.
Journal of ethnopharmacology, 249, 112405-112405 (2019-11-20)
The Chinese Herbal Prescription JieZe-1(JZ-1), added and subtracted from Yihuang Decoction, a famous formula in the 12th year of Kangxi in Qing Dynasty, has a clear effect on Genital Herpes (GH) and no obvious adverse reactions occur clinically. JZ-1 also
Abhishek Sharma et al.
Pharmacological research, 158, 104894-104894 (2020-05-15)
Many flavonoids have various beneficial actions like anti-inflammatory, anti-carcinogenic properties and many other clinical conditions. Astilbin is one such flavanoid compound having many physiological as well as pharmacological actions. To summarize the important findings from the research conducted using astilbin

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