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Merck

A156

Supelco

(±)-N-Allylnormetazocin -hydrochlorid

analytical standard

Synonym(e):

(2α,6α)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol

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About This Item

Empirische Formel (Hill-System):
C17H23NO · HCl
CAS-Nummer:
Molekulargewicht:
293.83
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Arzneimittelkontrolle

regulated under CDSA - not available from Sigma-Aldrich Canada

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

Cl.[H]C1(C)C2Cc3ccc(O)cc3C1(C)CCN2CC=C

InChI

1S/C17H23NO.ClH/c1-4-8-18-9-7-17(3)12(2)16(18)10-13-5-6-14(19)11-15(13)17;/h4-6,11-12,16,19H,1,7-10H2,2-3H3;1H

InChIKey

ZTGMHFIGNYXMJV-UHFFFAOYSA-N

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Vân-Ly Phan et al.
Journal of neuroscience research, 79(4), 561-572 (2005-01-07)
The sigma1 receptor is a unique intracellular receptor whose activation results in an efficient modulation of several neurotransmitter responses. Its role as a target for the rapid nongenomic effects of neuro(active)steroids and the age-related diminutions in steroid levels suggested that
J Kitanaka et al.
Psychopharmacology, 203(4), 781-792 (2008-12-05)
The effects of sigma receptor antagonists on methamphetamine (METH)-induced stereotypy have not been examined. We examined the effects of sigma antagonists on METH-induced stereotypy in mice. The administration of METH (10 mg/kg) to male ddY mice induced stereotyped behavior consisting
José Francisco Navarro et al.
Psicothema, 24(3), 427-430 (2012-07-04)
Recently, sigma-1 receptor modulators have been considered drugs with an interesting therapeutic potential for the treatment of anxiety. However, there is no clear information in preclinical studies about the possible effects of sigma-1 ligands on anxiety in experimental animal models.
Mitsuo Tanabe
Neuropharmacology, 53(3), 406-414 (2007-07-17)
Using whole-cell voltage-clamp recordings, hyperpolarization-activated cation currents (Ih) were elicited with hyperpolarizing voltage jumps in CA1 pyramidal neurons of rat hippocampal slices, and the effects of phencyclidine (PCP) and some sigma ligands on Ih were studied. PCP concentration-dependently (0.1-100 microM)
Nobuaki Egashira et al.
European journal of pharmacology, 563(1-3), 149-154 (2007-03-14)
In the present study, we examined the involvement of the sigma1 receptor in the inhibitory effect of the selective serotonin reuptake inhibitor (SSRI) fluvoxamine, compared with that of paroxetine, on marble-burying behavior, which is an animal model of obsessive-compulsive disorder.

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