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Echinacosid

primary reference standard

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About This Item

Empirische Formel (Hill-System):
C35H46O20
CAS-Nummer:
82854-37-3
Molekulargewicht:
786.73
Beilstein:
4778612
MDL-Nummer:
MFCD00075695
UNSPSC-Code:
85151701
PubChem Substanz-ID:
329747352
NACRES:
NA.24

Qualität

primary reference standard

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

HWI

Anwendung(en)

food and beverages

SMILES String

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)[C@H]2OC(=O)\C=C\c5ccc(O)c(O)c5)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1

InChIKey

FSBUXLDOLNLABB-ISAKITKMSA-N

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Allgemeine Beschreibung

Echinacoside (ECH) is a typical phenylethanoid glycoside. It is known to contain multiple unstable chemical bonds and high reactive functional groups which aids to pathways involving degradation and metabolism. It is isolated from the stems of Cistanches salsa. It is a crude drug mostly used as antisenium and antifatigue agents.
Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

Reference Standard in the analysis of herbal medicinal products

Biochem./physiol. Wirkung

Caffeic acid glycoside found in herbal medicine. Potential therapeutic for Parkinson′s disease.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
HWI00768-1
HWI00768-1
HWI00768

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Chlorogensäure Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2202

Chlorogensäure

Echinacoside rescues the SHSY5Y neuronal cells from TNFalpha-induced apoptosis.
Deng M
European Journal of Pharmacology, 505(1-3), 11-18 (2004)
Wenjun He et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 34(4), 476-479 (2009-05-23)
The paper reviews the recent developments in pharmacological activities of echinacoside (ECH). ECH is a phenylethanoid glycoside isolated and purified from the stems of Cistanche salsa, a parasitic plant native to northwest China, which is used as a traditional Chinese
Toshio Morikawa et al.
Journal of natural medicines, 68(3), 561-566 (2014-04-22)
Acylated phenylethanoid glycosides, echinacoside (1) and acteoside (2), principal constituents in stems of Cistanche tubulosa (Orobanchaceae), inhibited the increase in postprandial blood glucose levels in starch-loaded mice at doses of 250-500 mg/kg p.o. These compounds (1 and 2) also significantly improved
Dong-Mi Shin et al.
Archives of pharmacal research, 37(6), 803-812 (2013-10-03)
Echinacea purpurea has been shown to have anti-diabetic activities; for example, it activates peroxisome proliferator-activated receptor γ (PPARγ) and increases insulin-stimulated glucose uptake. Adipogenesis has been used to study the insulin signaling pathway and to screen anti-diabetic compounds. The present
Ivan Kováč et al.
The Journal of pharmacy and pharmacology, 67(1), 117-125 (2014-09-23)
Although the exact underlying mechanisms are still unknown, Plantago lanceolata L. (PL) water extracts are frequently used to stimulate wound healing and to drain abscesses. Therefore, in this experimental study the effect of PL water extract on skin wound healing was

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