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MAB5674

Sigma-Aldrich

Anti-Plectin Antibody, Clone 10F6

clone 10F6, Chemicon®, from mouse

Synonym(e):

Plackin

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

purified antibody

Antikörper-Produkttyp

primary antibodies

Klon

10F6, monoclonal

Speziesreaktivität

mouse, human, rat

Hersteller/Markenname

Chemicon®

Methode(n)

immunohistochemistry: suitable
western blot: suitable

UniProt-Hinterlegungsnummer

P30427

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ACTC1(70) , ACTG1(71)

Allgemeine Beschreibung

The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5′ exons to the first constant exon, which generates transcript variants that encode distinct isoforms

Spezifität

Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Reactivity with other species has not been tested.

Immunogen

Gel-purified C5 Cell plectin

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurodegenerative Krankheiten

Neuronen- & Gliamarker
Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Optimal working dilutions must be determined by the end user.

Qualität

Routinely tested on rat brain tissue lysate

Zielbeschreibung

300-500 kDa

Physikalische Form

Format: Purified
Purified in PBS with 0.05% NaN3

Lagerung und Haltbarkeit

Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.

Hinweis zur Analyse

Control
rat brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Elena Ambrosini et al.
Glia, 41(3), 290-300 (2003-01-16)
Macrophage inflammatory protein-3alpha/CCL20 is a recently identified chemokine that binds to CCR6 and acts as a chemoattractant for memory/differentiated T-cells, B-cells, and immature dendritic cells. We have previously reported that CCL20 and CCR6 mRNAs are expressed in the CNS of
Sarah D Ackerman et al.
The Journal of experimental medicine, 215(3), 941-961 (2018-01-26)
Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS), which serves to protect and insulate axons for rapid neuronal signaling. In zebrafish and rodent models, we identify GPR56/ADGRG1 as a

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