Direkt zum Inhalt
Merck

MAB3632

Sigma-Aldrich

Anti-PPAR gamma 1 and 2 Antibody, phospho-specific (Ser112)

ascites fluid, Chemicon®

Synonym(e):

PPARgamma1 and 2

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

monoclonal

Speziesreaktivität

mouse, human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
immunocytochemistry: suitable
western blot: suitable

Isotyp

IgG1

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

phosphorylation (pSer112)

Angaben zum Gen

human ... PPARG(5468)

Spezifität

Recognizes phosphorylated Peroxisome Proliferator Activated Receptor (PPAR) gamma1 and gamma2.

Immunogen

Epitope: phospho-specific (Ser112)
Phosphorylated (serine 112) synthetic peptide from amino acids 107-121 of human PPAR gamma2 (identical to PPAR gamma1). No homology with PPAR alpha or PPAR beta.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Transkriptionsfaktoren
Use Anti-PPAR gamma 1 & 2 Antibody, phospho-specific (Ser112) (mouse monoclonal antibody) validated in ELISA, WB, ICC to detect PPAR gamma 1 & 2 also known as Peroxisome Proliferator Activated Receptor γ 1 & 2.
Western blot: 1:500-1:5,000 on endogenous and recombinant protein.

Immunocytochemistry: 1:500-1:5,000

ELISA: 1:500-1:5,000

Optimal working dilutions must be determined by the end user.

Physikalische Form

Ascites. Liquid. Contains no preservative.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Tobias B Huber et al.
Molecular and cellular biology, 23(14), 4917-4928 (2003-07-02)
Mutations of NPHS1 or NPHS2, the genes encoding nephrin and podocin, as well as the targeted disruption of CD2-associated protein (CD2AP), lead to heavy proteinuria, suggesting that all three proteins are essential for the integrity of glomerular podocytes, the visceral
Bo-Mi Kim et al.
International journal of molecular medicine, 43(1), 489-500 (2018-10-27)
Muscat Bailey A grape stalk is an organic waste produced in marked amounts during the vinification of grapes. Previous studies have indicated that grape stalk is rich in bioactive phenolic compounds, and exhibits antioxidant and UV‑protective activities. However, its effects
Larry A Denner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(47), 16725-35a-16725-35a (2012-11-24)
We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate cognitive performance. Since extracellular signal-regulated protein kinase mitogen-activated protein
Dalila El Ouarrat et al.
Cell metabolism, 31(1), 162-173 (2019-11-12)
Insulin resistance is a major factor in obesity-linked type 2 diabetes. PPARγ is a master regulator of adipogenesis, and small molecule agonists, termed thiazolidinediones, are potent therapeutic insulin sensitizers. Here, we studied the role of transcriptional co-activator with PDZ-binding motif
Keisuke Yanagida et al.
JCI insight, 3(24) (2018-12-21)
White adipose tissue (WAT) can dynamically expand and remodel through adipocyte hypertrophy and hyperplasia. The relative contribution of these 2 mechanisms to WAT expansion is a critical determinant of WAT function and dysfunction in obesity. However, little is known about

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