ABT148

Anti-Claudin-11 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Claudin-11, Oligodendrocyte-specific protein
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human
• Speziesreaktivität (Voraussage durch Homologie): chimpanzee (based on 100% sequence homology)
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_005593
• UniProt-Hinterlegungsnummer: O75508
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CLDN11(5010)

Beschreibung

Allgemeine Beschreibung

Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.

Spezifität

Other homologies: Mouse and Rat (93% sequence homology).

This antibody recognizes the cytoplasmic domain of Claudin-11.

Immunogen

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.

Anwendung

Research Category
Zellstruktur

Research Sub Category
ECM-Proteine

Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.

Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.

Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.

Qualität

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.

Zielbeschreibung

~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Human brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable