ABN342

Anti-FEZ2 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Fasciculation and elongation protein zeta-2, Zygin II, Zygin-2
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human, mouse
• Methode(n): immunofluorescence: suitable; western blot: suitable
• Isotyp: IgG
• UniProt-Hinterlegungsnummer: Q9UHY8
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... FEZ2(9637)

Beschreibung

Allgemeine Beschreibung

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

Immunogen

KLH-conjugated linear peptide corresponding to human FEZ2.

Anwendung

Research Category
Neurowissenschaft

Neurowissenschaft

Research Sub Category
Entwicklungsneurowissenschaft

Neuroregenerative Medizin

Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.

Immunofluorescence Analysis: 5 µg/mLfrom a representative lot detected FEZ2 in human brain tissue.

Qualität

Evaluated by Western Blot in 3T3 cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected FEZ2 in 15 µg of 3T3 cell lysate.

Zielbeschreibung

~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.

Physikalische Form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
3T3 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable