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Merck

AB5050P

Sigma-Aldrich

Anti-NMDAR1 Splice Variant C2 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

rat, mouse

Verpackung

antibody small pack of 25 μg

Hersteller/Markenname

Chemicon®

Methode(n)

immunohistochemistry: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

mouse ... Grin1(14810)
rat ... Grin1(24408)

Spezifität

Specific for the NMDAR1 containing the C2′ splice variant insert. The antibody does not recognize the NMDAR1 subunits of the NMDA receptor that do not contain the C2′ insert. By Western blot the antibody recognizes a protein with molecular weight of 120 kDa. Also labels a single higher molecular weight band that may be a posttranslationally modified form of the protein.

Immunogen

Peptide corresponding to the C-terminus of the rat NMDAR1 C2′ splice variant.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren
Detect NMDAR1 Splice Variant C2 using this Anti-NMDAR1 Splice Variant C2 Antibody validated for use in IH & WB.
Western blot: 1:2000 using ECL

Immunohistochemistry: 1:1000

Optimal working dilutions must be determined by the end user.

Physikalische Form

Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM) so some residual salt may also be present. Reconstitute with 50 μL of PBS. Contains no preservatives.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1


Analysenzertifikate (COA)

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Withdrawal from chronic intermittent alcohol exposure increases dendritic spine density in the lateral orbitofrontal cortex of mice.
McGuier, NS; Padula, AE; Lopez, MF; Woodward, JJ; Mulholland, PJ
Alcohol null
Intrauterine growth restriction due to uteroplacental insufficiency decreased white matter and altered NMDAR subunit composition in juvenile rat hippocampi.
Schober, ME; McKnight, RA; Yu, X; Callaway, CW; Ke, X; Lane, RH
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology null
Thorsten Pauly et al.
PloS one, 3(7), e2681-e2681 (2008-07-17)
Functional and structural alterations of clustered postsynaptic ligand gated ion channels in neuronal cells are thought to contribute to synaptic plasticity and memory formation in the human brain. Here, we describe a novel molecular mechanism for structural alterations of NR1

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