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AB3478

Sigma-Aldrich

Anti-Defensin β3 Antibody

Chemicon®, from rabbit

Synonym(e):

BD-3, hBD-3

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable
western blot: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

Allgemeine Beschreibung

Beta Defensin-3 is a novel 5 kDa nonhemolytic antimicrobial protein peptide which may be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung (such as cystic fibrosis).

Spezifität

Recognizes the 5-6 kDa human Defensin-3, beta protein.

Immunogen

A synthetic peptide consisting of amino acids 23-33 [GIINTLQKYYC] of the human beta-defensin-3 protein.

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Immunoglobuline & Immunologie
Anti-Defensin Antibody, β3 is an antibody against Defensin for use in ELISA & WB.
Western blotting: Tricine-SDS- PAGE gels recommended: 1:500-1:1,000, migrates as a 5-6kDa band; Tricine-SDS-urea PAGE gels: Native Beta Defensin 3 migrates as a 9kDa band; the larger size is because of the reduction of the three cysteine bridges present in the peptide protein

Optimal working dilutions must be determined by the end user.

Physikalische Form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Lagerung und Haltbarkeit

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Seiko Takeda et al.
Journal of toxicologic pathology, 26(1), 35-40 (2013-06-01)
Defensins are generally implicated in the quick resistance of epithelial surfaces to microbials; however, recent reports have indicated that defensins also have unknown purposes in relation to noninfectious diseases. In this study, the localization patterns of anti-microbial peptides, β defensins

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