A calcium-dependent lectin with affinity for furanosides, such as galactofuranosyl in bacterial arabinogalactans. 30kD of apparent molecular weight of Omentin migrate at 40-kD under reducing conditions due to glycosylation. Omentin, a novel visceral fat depot-specific secretory protein, enhance insulin-stimulated glucose transport in subcutaneous as well as omental adipocytes and may therefore be implicated in the pathogenesis of obesity.
Spezifität
Recognizes Omentin in western blotting.
Immunogen
Epitope: Amino acids 95-115 of Human Omentin.
Synthetic peptide: TVGDRWSSQQGSKADYPEGDG, corresponding to amino acids 95-115 of Human Omentin.
Anwendung
Anti-Omentin Antibody detects level of Omentin & has been published & validated for use in ELISA & WB.
Western blot: 1:2,000-1:5,000 using ECL. Reacted with the ~40kDa Omentin His-tagged protein. Suggested blocking and dilution buffer is PBST with 0.05% Tween-20 and 5% skim milk. Suggested incubation time is 1 hour at room temperature.
ELISA, direct and indirect: 1:2,000-1:5,000.
Zielbeschreibung
30-40 kDa
Physikalische Form
Format: Purified
Liquid in PBS, pH7.4. Contains no preservatives.
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Lagerklassenschlüssel
12 - Non Combustible Liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Obesity is a significant risk factor for the development of type 2 diabetes mellitus (T2DM). Adipose tissue dysfunction can affect the pool of circulating exosomal miRNAs, driving concomitant disease in obesity. These exosomal miRNAs can reflect adipose tissue functionality, thus
Advanced ovarian cancer usually spreads to the omentum. However, the omental cell-derived molecular determinants modulating its progression have not been thoroughly characterized. Here, we show that circulating ITLN1 has prognostic significance in patients with advanced ovarian cancer. Further studies demonstrate
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