581004

Telomerase Inhibitor III, Sodium Salt

The Telomerase Inhibitor III, Sodium Salt controls the biological activity of Telomerase. This small molecule/inhibitor is primarily used for Cell Structure applications.

• Synonym(e): TAG-6, 5ʹ-d(TTAGGG)-3ʹ
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Form: lyophilized
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated (hygroscopic); protect from light
• Löslichkeit: water: soluble
• Versandbedingung: wet ice
• Lagertemp.: −70°C

Beschreibung

Allgemeine Beschreibung

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomer mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM.

A short, cell-permeable hexameric phosphorothioate oligonucleotide (PS-ODN) telomere mimic that inhibits telomerase activity in cell lysates and lengthens cell doubling time in vitro and in vivo at concentrations of less than 2.5 µM. Note: 150 nmol = 285 µg.

M.W. ~1900.

Biochem./physiol. Wirkung

Cell permeable: yes

Primary Target
Telomerase activity in cell lysates

Product competes with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Sequenz

5′-d(TTAGGG)-3′

Sonstige Hinweise

Mata, J.E., et al. 1997. Toxicol. Appl. Pharmacol. 144, 189.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable