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PhosphoDetect Anti-SAPK/JNK (pThr¹⁸³, Tyr¹⁸⁵) Rabbit pAb

liquid, Calbiochem®

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

liquid

Enthält

≤0.1% sodium azide as preservative

Speziesreaktivität

Drosophila, chicken, Caenorhabditis elegans, human, mouse, rat

Hersteller/Markenname

Calbiochem®

Lagerbedingungen

OK to freeze
avoid repeated freeze/thaw cycles

Isotyp

IgG

Versandbedingung

wet ice

Lagertemp.

−70°C

Posttranslationale Modifikation Target

phosphorylation (pThr183/pTyr185)

Angaben zum Gen

human ... MAPK8(5599)

Allgemeine Beschreibung

Rabbit polyclonal antibody adsorbed against non-phosphopeptide corresponding to the immunogen phosphorylation site, followed by immunoaffinity chromatography. Recognizes the ~49 kDa JNK1/SAPK1 protein and the ~55 kDa JNK2/SAPK2 protein phosphorylated at Thr183 and Tyr185.
Recognizes the ~49 kDa SAPK1 protein and the ~55 kDa SAPK2 protein phosphorylated at Thr183 and Tyr185.
  • Antibody Target Gene Symbol: MAPK8, MAPK9
  • Target Synonym: AI849689, C-JUN N-TERMINAL KINASE1, JNK, JNK1, JNK1 PROTEIN KINASE, JNK1A2, JNK21B1/2, p46JNK1, p46JNK1 ALPHA, PRKM8, Sapk gamma, SAPK P46, SAPK1, SAPK1/JNK, STRESS-ACTIVATED PROTEIN KINASE-LIKE KINASE, AI851083, Jnk p54, Jnk p55, JNK-55, JNK2, JNK2A, Jnk2a2, JNK2ALPHA, JNK2B, JNK2BETA, JUNKINASE, p54a, p54aSAPK, PRKM9, SAPK, SAPK ALPHA, SAPK ALPHA 1
  • Entrez Gene Name: mitogen-activated protein kinase 8
  • Hu Entrez ID: 5601
  • Mu Entrez ID: 26420
  • Rat Entrez ID: 50658
    • This PhosphoDetect Anti-SAPK/JNK (pThr¹⁸³, Tyr¹⁸⁵) Rabbit pAb is validated for use in WB, IHC for the detection of SAPK/JNK (pThr¹⁸³, Tyr¹⁸⁵).

    Immunogen

    Human
    a synthetic phosphopeptide corresponding to amino acids surrounding the Thr¹⁸³ and Tyr¹⁸⁵ phosphorylation sites of human SAPK/JNK

    Anwendung

    Immunoblotting (1:1000)

    Immunohistochemistry (see comments)

    Warnhinweis

    Toxicity: Standard Handling (A)

    Physikalische Form

    In Dulbecco′s PBS (without Mg2+ and Ca2+), 50% glycerol, 1 mg/ml BSA, pH 7.3.

    Rekonstituierung

    Following initial thaw, aliquot and freeze (-70°C).

    Sonstige Hinweise

    Fanger, G.R., et al. 1999. Histol. Histopathol.14, 887.
    Gabai, V.L., et al. 1998. FEBS Lett.438, 1.
    Specific for the dually phosphorylated form of JNK/SAPK containing a phosphate on threonine 183 and tyrosine 185. This antibody has also been reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the proper working dilution.

    Rechtliche Hinweise

    CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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    Lagerklassenschlüssel

    12 - Non Combustible Liquids

    WGK

    WGK 1

    Flammpunkt (°F)

    Not applicable

    Flammpunkt (°C)

    Not applicable

    Analysenzertifikate (COA)

    Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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