454565

Methyl Arachidonyl Fluorophosphonate - Calbiochem

• Synonym(e): Methyl Arachidonyl Fluorophosphonate - Calbiochem, MAFP, cPLA2α Inhibitor III
• Empirische Formel (Hill-System): C₂₁H₃₆FO₂P
• Molekulargewicht: 370.48
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥98% (TLC)
• Qualitätsniveau: 100
• Form: liquid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Versandbedingung: wet ice
• Lagertemp.: −70°C

Beschreibung

Allgemeine Beschreibung

This product has been discontinued.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not of secretory PLA₂.

A selective, active site-directed, irreversible inhibitor of both calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A₂ (PLA₂) but not secretory PLA₂.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
calcium-dependent and calcium-independent cytosolic (85 kDa) phospholipase A2 (PLA2)

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Standard Handling (A)

Physikalische Form

In methyl acetate.

Rekonstituierung

Prior to use, evaporate the methyl acetate and resuspend in high quality chloroform. Aliquot and immediately evaporate the chloroform. Store aliquots at -70°C. Reconstitute in DMSO just prior to use.

Sonstige Hinweise

Balsinde, J., and Dennis, E.A. 1996. J. Biol. Chem. 271, 6758.
Lio, Y.C., et al. 1996. Biochim. Biophys. Acta1302, 55.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany