341597

FGF-II, Mouse, Recombinant, E. coli

• Synonym(e): mFGF-II, Fibroblast Growth Factor-II
• UNSPSC-Code: 12352202

Eigenschaften

• Assay: ≥95% (SDS-PAGE)
• Qualitätsniveau: 100
• Form: lyophilized solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze
• Verunreinigungen: ≤0.1 ng/μg Endotoxins (ng/μg FGF-2)
• Farbe: white
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Full-length, recombinant, mouse basic fibroblast growth factor expressed in E. coli. A multi-functional factor with chemotactic activity for numerous cell types. It plays a role in the proliferation of neuronal precursors and in neuronal differentiation. A potent angiogenic factor both in vivo and in vitro. Activates phospholipase D in endothelial cells. Mouse FGFII shares 95% identity with human FGFII. Useful for studies of cell activation and signaling.

Biochem./physiol. Wirkung

ED₅₀: ≤0.5 ng/ml as determined by the dose-dependent proliferation of BALB/3T3 cells.

Warnhinweis

Toxicity: Standard Handling (A)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Avoid freeze/thaw cycles of solutions.

Reconstitute to 100 µg/ml with sterile H₂O.

Sonstige Hinweise

Coulier, F. et al. 1997. J. Mol Evol.44, 43.
Claus, P. et al., 2003. J. Biol. Chem.278, 749.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 10-13 - German Storage Class 10 to 13