260575

1-Deoxymannojirimycin, Hydrochloride

A specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.

• Synonym(e): 1-Deoxymannojirimycin, Hydrochloride, DMJ, 1,5-Dideoxy-1,5-imino-D-mannitol, HCl
• Empirische Formel (Hill-System): C₆H₁₃NO₄ · xHCl
• CAS-Nummer: 84444-90-6
• Molekulargewicht: 163.17 (free base basis)
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (TLC)
• Form: crystalline solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; desiccated (hygroscopic)
• Farbe: white
• Löslichkeit: ethanol: 1 mg/mL; water: 1 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C
• InChI: 1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4-,5-,6-/m1/s1
• InChIKey: LXBIFEVIBLOUGU-KVTDHHQDSA-N

Beschreibung

Allgemeine Beschreibung

A specific α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.

Special α-mannosidase I inhibitor that blocks conversion of high mannose to complex oligosaccharides.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
α-mannosidase-I

Product does not compete with ATP.

Reversible: no

Verpackung

Packaged under inert gas

Warnhinweis

Toxicity: Harmful (C)

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 6 months at -20°C.

Sonstige Hinweise

Suzuki, S.S., and Piette, L.H. 1993. J. Cell. Biochem.51, 181.
Fuhrmann, U., et al. 1984. Nature307, 755.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable