764787

Poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide)

average M_n (1,000-1,000-1,000), lactide:glycolide 50:50

• Synonym(e): PLGA-PEG-PLGA
• UNSPSC-Code: 12162002
• NACRES: NA.23

Eigenschaften

• Beschreibung: typical PEG PDI<1.1; overall PDI<1.2 (THF, PEO)
• Form: liquid
• Zufuhrverhältnis: lactide:glycolide 50:50
• Mol-Gew.: PEG average M_n 1,000; PLGA average M_n 2000; average M_n (1,000-1,000-1,000)
• Zeitrahmen für den Abbau: 1-2 weeks
• PDI: <1.2
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs.

Anwendung

Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs.

Leistungsmerkmale und Vorteile

Biocompatible, degradable, thermosensitive, high stability, small size (<200 nm) and properties can be easily modified.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable