586579

5-Fluor-2-oxindol

97%

• Synonym(e): 5-Fluoro-1,3-dihydroindol-2-one, 5-Fluoro-2,3-dihydro-2-oxoindole
• Empirische Formel (Hill-System): C₈H₆FNO
• CAS-Nummer: 56341-41-4
• Molekulargewicht: 151.14
• MDL-Nummer: MFCD02179598
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24881126
• NACRES: NA.22

Eigenschaften

• Assay: 97%
• mp (Schmelzpunkt): 143-147 °C (lit.)
• SMILES String: Fc1ccc2NC(=O)Cc2c1
• InChI: 1S/C8H6FNO/c9-6-1-2-7-5(3-6)4-8(11)10-7/h1-3H,4H2,(H,10,11)
• InChIKey: DDIIYGHHUMKDGI-UHFFFAOYSA-N

Beschreibung

Anwendung

Reactant for preparation of:

• Glycogen synthase kinase 3 beta (GSK-3β) inhibitors
• Antitumor agents
• Cyclooxygenase 1/2 (COX-1/2) and 5-lipoxygenase (5-LOX) inhibitors
• Multitargeted Receptor Tyrosine Kinase Inhibitors
• Non-peptide thrombopoietin (TPO) receptor ligands
• Aurora kinase inhibitors
• Inhibitors of cyclin-dependent kinase CDK2/cyclin A
• Selective norepinephrine reuptake inhibitors
• B-cell lymphoma-extra large molecule (Bcl-XL) inhibitor Z36
• Inducers of NAD(P)H-quinone oxidoreductase 1 (NQO1)

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)