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47296

o-Fluor-L-phenylalanin

Name: <I>o</I>-Fluor-<SC>L</SC>-phenylalanin
Brand: ALDRICH

puriss., ≥99.0% (sum of enantiomers, HPLC)

Synonym(e):

2-Fluor-L-phenylalanin

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About This Item

Empirische Formel (Hill-System):

C₉H₁₀FNO₂

CAS-Nummer:

19883-78-4

Molekulargewicht:

183.18

Beilstein:

2805791

MDL-Nummer:

MFCD00066448

UNSPSC-Code:

12352200

PubChem Substanz-ID:

24870852

Qualität

puriss.

Assay

≥99.0% (sum of enantiomers, HPLC)

Optische Aktivität

[α]20/D −14±1°, c = 1% in H₂O

Optische Reinheit

enantiomeric ratio: ≥99.5:0.5 (TLC)

SMILES String

N[C@@H](Cc1ccccc1F)C(O)=O

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

264687/1

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Does the anabolic metabolism of L-[2-18F]fluorophenylalanine and L-[2,6-3H]phenylalanine differ in the cerebrum and the cerebellum?

H Nakamichi et al.

Nuclear medicine and biology, 21(7), 959-962 (1994-10-01)

The anabolism of isotopically labeled amino acids was compared between the cerebrum and the cerebellum in conscious rat at three feeding conditions. After L-[2-18F]fluorophenylalanine and L-[2,6-3H]phenylalanine injections, the incorporation rate of both radioactivity into protein fraction showed no difference between

Structure-activity relationships among substituted N-benzoyl derivatives of phenylalanine and its analogs in a microbial antitumor prescreen I: Derivatives of o-fluoro-DL-phenylalanine.

T T Otani et al.

Journal of pharmaceutical sciences, 71(2), 214-216 (1982-02-01)

Twelve derivatives of 0-fluoro-dl-phenylalanine containing fluorine, chlorine, methoxy, and nitro radicals in various positions of the aromatic ring of the benzoyl group were prepared and tested in a Lactobacillus casei system. It was found that most substitutions in the benzoyl

Feasibility of fluorine-18-fluorophenylalanine for tumor imaging compared with carbon-11-L-methionine.

K Kubota et al.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 37(2), 320-325 (1996-02-01)

L-[methyl-11C]methionine (11C-Met) is a useful tracer for tumor imaging with PET. The drawbacks include a short half-life and high physiological accumulation in abdominal organs. To overcome these shortfalls, the feasible use of [18F]fluorophenylalanine (18F-Phe), which shares the same amino acid

Uncovering the enzymatic pKa of the ribosomal peptidyl transferase reaction utilizing a fluorinated puromycin derivative.

Kensuke Okuda et al.

Biochemistry, 44(17), 6675-6684 (2005-04-27)

The ribosome-catalyzed peptidyl transferase reaction displays a complex pH profile resulting from two functional groups whose deprotonation is important for the reaction, one within the A-site substrate and a second unidentified group thought to reside in the rRNA peptidyl transferase

Enantiospecific synthesis of 2-[18F]fluoro-L-phenylalanine and 2-[18F]fluoro-L-tyrosine by isotopic exchange.

Johnny Castillo Meleán et al.

Organic & biomolecular chemistry, 9(3), 765-769 (2010-11-23)

2-[(18)F]Fluoro-L-phenylalanine and 2-[(18)F]fluoro-L-tyrosine have been developed as promising radiopharmaceuticals for molecular imaging using positron emission tomography (PET). However, the lack of a convenient radiosynthetic pathway has limited their practical use. In this work a new three-step nucleophilic synthesis of these

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