149837

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydrochinolin

≥99%, for peptide synthesis

• Synonym(e): 1,2-Dihydro-2-ethoxychinolin-1-carbonsäure-ethylester, N-Ethoxycarbonyl-2-ethoxy-1,2-dihydrochinolin, EEDQ
• Empirische Formel (Hill-System): C₁₄H₁₇NO₃
• CAS-Nummer: 16357-59-8
• Molekulargewicht: 247.29
• Beilstein: 533048
• EG-Nummer: 240-418-2
• MDL-Nummer: MFCD00006703
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24848976
• NACRES: NA.22

Eigenschaften

• product name: 2-Ethoxy-1-ethoxycarbonyl-1,2-dihydrochinolin, ≥99%
• Assay: ≥99%
• Form: solid
• Eignung der Reaktion: reaction type: Coupling Reactions
• mp (Schmelzpunkt): 62-67 °C (lit.)
• Anwendung(en): peptide synthesis
• Lagertemp.: 2-8°C
• SMILES String: CCOC1C=Cc2ccccc2N1C(=O)OCC
• InChI: 1S/C14H17NO3/c1-3-17-13-10-9-11-7-5-6-8-12(11)15(13)14(16)18-4-2/h5-10,13H,3-4H2,1-2H3
• InChIKey: GKQLYSROISKDLL-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline(EEDQ) is a stable, and readily available reagent used to prepare amides and peptides in high yields. At ambient temperature, EEDQ is soluble in an aqueous medium containing organic solvents but insoluble in water. It is used as a coupling agent in peptide synthesis.

Anwendung

2-Ethoxy-1-ethoxycarbonyl-1,2-dihydroquinoline is used as a coupling agent:

• In the regioselective quaternization of chitosan and its amphiphilic derivatives.
• In the preparation of amide-type S-MA derivative-modified QCM sensors.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves