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Merck

KCNA5

potassium voltage-gated channel, shaker-related subfamily, member 5

Synonyme:
ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(3741) Summary: Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012]
  • Mouse(16493) potassium voltage-gated channel, shaker-related subfamily, member 5
  • Rat(25470) potassium voltage-gated channel, shaker-related subfamily, member 5
  • cow(508960) potassium voltage-gated channel, shaker-related subfamily, member 5
  • domestic cat(101100573) potassium voltage-gated channel, shaker-related subfamily, member 5
  • dog(403995) potassium voltage-gated channel, shaker-related subfamily, member 5
  • chicken(395115) potassium voltage-gated channel, shaker-related subfamily, member 5
  • naked mole-rat(101715453) potassium voltage-gated channel, shaker-related subfamily, member 5
  • domestic guinea pig(100732253) potassium voltage-gated channel, shaker-related subfamily, member 5
  • Domestic Rabbit(100008684) potassium voltage-gated channel, shaker-related subfamily, member 5
  • sheep(101111448) potassium voltage-gated channel, shaker-related subfamily, member 5

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-KCNA5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-KCNA5 antibody produced in mouse, clone S7-45, 1 mg/mL, purified immunoglobulin,
Speziesreaktivität
human, mouse, rat
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-Potassium Channel Kv1.5 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Speziesreaktivität
mouse, rat
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Guanidin -hydrochlorid, for molecular biology, ≥99%,
Spezies
human
Guanidin -hydrochlorid, ≥98%,
Spezies
human
Guanidin -hydrochlorid, organic base and chaeotropic agent, ≥99% (titration),
Spezies
human
Guanidin -hydrochlorid, ,
Spezies
human
Guanidin -hydrochlorid -Lösung, Colorless liquid, 7.8 - 8.3 M, pH- 4.5 - 5.5,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human KCNA5,
Spezies
human