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AKR1B1

aldo-keto reductase family 1, member B1 (aldose reductase)

Synonyme:
ADR, ALDR1, ALR2, AR
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(231) Summary: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]
  • Rat(24192) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Domestic Rabbit(100009122) aldo-keto reductase family 1, member B1 (aldose reductase)
  • naked mole-rat(101720124) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic guinea pig(100718017) aldo-keto reductase family 1, member B1 (aldose reductase)
  • Zebrafish(415138) aldo-keto reductase family 1, member B1 (aldose reductase)
  • domestic cat(101095406) aldo-keto reductase family 1, member B1 (aldose reductase)
  • cow(317748) aldo-keto reductase family 1, member B1 (aldose reductase)
  • dog(607537) aldo-keto reductase family 1, member B1 (aldose reductase)
  • sheep(101120824) aldo-keto reductase family 1, member B1 (aldose reductase)

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
Anti-AKR1B1 antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
dog, human, mouse, pig, rat
Anwendung
western blot
Anti-AKR1B1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
guinea pig, horse, human, mouse, rat
Anwendung
immunohistochemistry
western blot
Anti-AKR1B1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
(±)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carbonsäure, 97%,
Spezies
rat
Hippursäure, 98%,
Spezies
rat
Fluoren-9-Carboxylsäure, 96%,
Spezies
rat
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human AKR1B1,
Spezies
human