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ACTN2

actinin, alpha 2

Synonyme:
CMD1AA
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(88) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
  • Mouse(11472) actinin alpha 2
  • Rat(291245) actinin alpha 2
  • naked mole-rat(101721630) actinin, alpha 2
  • domestic guinea pig(100712846) actinin, alpha 2
  • chicken(396263) actinin, alpha 2
  • Zebrafish(641575) actinin, alpha 2
  • domestic cat(101101415) actinin, alpha 2
  • dog(479191) actinin, alpha 2
  • cow(536607) actinin, alpha 2
  • Horse(100033870) actinin, alpha 2
  • Domestic Rabbit(100350274) actinin, alpha 2
  • sheep(101116372) actinin, alpha 2

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Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-alpha Actinin 2 Antibody, clone 1E11, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, mouse, rat
Anwendung
immunocytochemistry
immunofluorescence

immunohistochemistry

western blot
Anti-Actinin α antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-ACTN2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-ACTN2, affinity isolated antibody,
Speziesreaktivität
guinea pig, human, mouse, rabbit, rat
Anwendung
immunohistochemistry
western blot
Anti-ACTN2 (AB1) antibody produced in rabbit, IgG fraction of antiserum,
Speziesreaktivität
human, mouse, rat
Anwendung
western blot

Proteins

Produktnummer
Beschreibung
Spezies
α-Actinin aus Hühner-Muskelmagen, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Spezies
mouse, chicken, rat, human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human ACTN2,
Spezies
human
MISSION® esiRNA, targeting mouse Actn2,
Spezies
mouse