SRP0697

TAU-316 Protein

recombinant

• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.77

Propriétés

• Produit recombinant: expressed in E. coli
• Pureté: 70-95% (SDS-PAGE)
• Forme: frozen liquid
• Poids mol.: ~39 kDa
• Concentration: 0.2 μg/μL
• Numéro d'accès: P10636-3
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Informations sur le gène: human ... MAPT(4137)

Description

Application

Useful for kinase assay and Western blot.

Actions biochimiques/physiologiques

Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type ⁽¹⁾. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer′s disease, Pick′s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy ⁽²⁾.

Séquence

Full Length

Reconstitution

Formulated in 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM PMSF, with 25% glycerol.

Stockage et stabilité

Store in aliquots at -70°C. Avoid freeze/thaw cycles.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable