SAB4504536

Anti-phospho-Src (pTyr⁴¹⁸) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-ASV, Anti-SRC1, Anti-THC6, Anti-c-SRC, Anti-p60-Src
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 59 kDa
• Espèces réactives: human, mouse, rat
• Concentration: ~1 mg/mL
• Technique(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• Numéro d'accès NCBI: P12931
• Numéro d'accès UniProt: P12931
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: phosphorylation (pTyr418)
• Informations sur le gène: human ... SRC(6714)

Description

Description générale

SRC (proto-oncogene, non-receptor tyrosine kinase) belongs to the Src family kinases (SFKs). It contains an amino-terminal domain, conserved Src-homology domains (SH2 and SH3), a tyrosine kinase domain and the carboxyl-terminus. This gene is located on human chromosome 20q11.

Immunogène

The antiserum was produced against synthesized peptide derived from human Src around the phosphorylation site of Tyr418.

Immunogen Range: 386-435

Application

Anti-phospho-Src (pTyr418) antibody has been used in immunofluorescence.

Actions biochimiques/physiologiques

SRC (proto-oncogene, non-receptor tyrosine kinase) controls early HIV-1 (human immunodeficiency virus 1) infection post-entry. This gene participates in fundamental physiological and pathological processes like carcinogenesis and tumor progression. Src kinase activity helps in the migration of endothelial cells.

Caractéristiques et avantages

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Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable