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Key Documents

SAB4502043

Sigma-Aldrich

Anti-OPRD1 antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

δ-opioid receptor, δ-type opioid receptor, K56, MSL-2, OPRD

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About This Item

Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

antigen 40 kDa

Espèces réactives

human

Concentration

~1 mg/mL

Technique(s)

ELISA: 1:5000
western blot: 1:500-1:1000

Numéro d'accès NCBI

P41143

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... OPRD(4985)

Description générale

Anti-OPRD1 antibody detects endogenous levels of total OPRD1 protein.
The OPRD1 (opioid receptor δ1) gene is mapped to human chromosome 1p35.3 and encodes for a G-protein-coupled receptor. It is abundantly expressed in peripheral tissues.

Immunogène

The antiserum was produced against synthesized peptide derived from human OPRD1.

Immunogen Range: 311-360

Actions biochimiques/physiologiques

OPRD1 (opioid receptor δ1) is associated with cognitive function and mood driven behavior. Anxiolytic and antidepressant actions are brought about when specific agonists bind to the OPRD1 gene. δ-opioid receptor (DOR) is known to be involved in the progression and development of specific tumours (malignant). Upregulation of this gene is observed in breast cancer, and thus, it can serve as an important therapeutic marker.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

nwg

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Ann M Manzardo et al.
Gene, 560(2), 184-194 (2015-02-07)
Alcoholism arises from combined effects of multiple biological factors including genetic and non-genetic causes with gene/environmental interaction. Intensive research and advanced genetic technology has generated a long list of genes and biomarkers involved in alcoholism neuropathology. These markers reflect complex
Louis Gendron et al.
Pharmacological reviews, 68(3), 631-700 (2016-06-28)
Opioids are among the most effective analgesics available and are the first choice in the treatment of acute severe pain. However, partial efficacy, a tendency to produce tolerance, and a host of ill-tolerated side effects make clinically available opioids less
Yang-Chao Wei et al.
Oncology reports, 36(5), 2579-2586 (2016-10-26)
δ‑opioid receptor (DOR) belongs to the family of G protein‑coupled receptors (GPCRs). Numerous studies have shown that DOR is widely distributed in human peripheral tissues and is closely related to the development and progression of certain malignant tumours. However, there is controversy in
Huihui Ji et al.
PloS one, 12(3), e0172335-e0172335 (2017-03-03)
Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder in the elderly. OPRD1 encodes the delta opioid receptor, a member of the opioid family of G-protein-coupled receptors. In the current study, we

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