SAB3500310

Anti-IL-23 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-IL-27 p28, Anti-Interleukin-27
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: predicted mol wt 21 kDa
• Espèces réactives: human, mouse
• Technique(s): immunocytochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• Numéro d'accès NCBI: AAH66268
• Numéro d'accès UniProt: Q9NPF7
• Conditions d'expédition: dry ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... IL23A(51561)

Description

Description générale

IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.

Immunogène

IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.

Application

Anti-IL-23 antibody has been used in western blotting.

Actions biochimiques/physiologiques

The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Liaison

The action of this antibody can be blocked using blocking peptide SBP3500310.

Forme physique

Supplied in PBS with 0.02% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable