R3250

Retinyl acetate

synthetic, matrix dispersion, 475,000-650,000 USP units/g

• Synonyme(s) : Acétate de rétinol
• Formule empirique (notation de Hill): C₂₂H₃₂O₂
• Numéro CAS: 127-47-9
• Poids moléculaire : 328.49
• Numéro Beilstein : 1915439
• Numéro CE : 204-844-2
• Numéro MDL: MFCD00019413
• Code UNSPSC : 12352205
• eCl@ss : 34058009
• ID de substance PubChem : 57654589
• Nomenclature NACRES : NA.79

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 200
• Forme: matrix dispersion
• Activité spécifique: 475,000-650,000 USP units/g
• Couleur: yellow
• Pf: 57-58 °C
• Température de stockage: −20°C
• Chaîne SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• Clé InChI: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Description

Description générale

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain. Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate.

Application

Retinyl acetate has been used:

• a control diet to study its effect at different developmental periods in fish larvae
• to study its inhibitory effects on Mycobacterium avium subspecies paratuberculosis (MAP) strains
• as an internal standard in high performance liquid chromatography (HPLC) to quantify vitamin A in fortified milk

Actions biochimiques/physiologiques

Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as required. Retinyl acetate is used in a wide range of biological applications. It acts as a chemopreventive agent. Retinyl acetate also has antineoplastic property.

Forme physique

Dispersion in cornstarch-gelatin matrix. Oil dispersible

Remarque sur l'analyse

Activity based on HPLC comparison to USP standard.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H360D,H413
• Conseils de prudence: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Classification des risques: Aquatic Chronic 4 - Repr. 1B
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type ABEK (EN14387) respirator filter