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G6019

Sigma-Aldrich

Glyceraldehyde-3-phosphate Dehydrogenase from human erythrocytes

lyophilized powder, 50-150 units/mg protein

Synonyme(s) :

D-Glyceraldehyde 3-phosphate:NAD+ oxidoreductase (phosphorylating), GAPDH

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About This Item

Numéro CAS:
9001-50-7
Numéro de classification (Commission des enzymes):
1.2.1.12 (BRENDA, IUBMB)
Numéro MDL:
MFCD00131203
Code UNSPSC :
12352204
Nomenclature NACRES :
NA.54

Forme

lyophilized powder

Niveau de qualité

200

Activité spécifique

50-150 units/mg protein

Composition

Protein, 40-70% biuret

Numéro d'accès UniProt

P04406

Activité étrangère

3-Phosphoglyceric phosphokinase ≤2%

Température de stockage

−20°C

Informations sur le gène

human ... GAPDH(2597)

Actions biochimiques/physiologiques

Glyceraldehyde-3-phosphate dehydrogenase catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate as part of glycolysis. It has also been shown to have roles in initiation of apoptosis, transcription activation and the shuttling of ER to Golgi vesicles<<<18,New>>>.

Définition de l'unité

One unit will reduce 1.0 μmole of 3-phosphoglycerate to D-glyceraldehyde 3-phosphate per min in a coupled system with 3-phosphoglyceric phosphokinase at pH 7.6 at 25 °C.

Forme physique

Lyophilized powder containing sodium citrate buffer salts

Inhibiteur

Réf. du produit
Description
Tarif

I2512

Sodium iodoacetate, ≥98%

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Kyle L Sunderland et al.
Journal of strength and conditioning research, 27(1), 1-7 (2012-10-23)
The purpose of this study was to investigate how age and 1 week of conventional resistance exercise affects commonly used housekeeping gene (HKG) messenger RNAs (mRNAs) in skeletal muscle. Ten college-aged (18-25 years) and 10 older (60-76 years) men completed
Shunqing Liang et al.
Veterinary immunology and immunopathology, 150(3-4), 198-205 (2012-10-23)
Edwardsiella tarda is a Gram-negative pathogen which causes systemic infection in turbot. The increasing frequency of edwardsiellosis in turbot farming has stressed the need to understand the immune responses of fish, for the further development of prevention and control strategies.
Qiao Liu et al.
Acta crystallographica. Section F, Structural biology and crystallization communications, 68(Pt 8), 978-980 (2012-08-08)
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an important enzyme in the glycolytic pathway. In addition to its conventional metabolic role, GAPDH has been identified to possess diverse cellular functions. In this study, glyceraldehyde-3-phosphate dehydrogenase 3, the third isoform of GAPDH from Saccharomyces
Soya S Sam et al.
Pathology, research and practice, 208(12), 705-707 (2012-10-13)
Isolation of DNA from formalin-fixed, paraffin-embedded (FFPE) tissue remains a laborious task for clinical laboratories and researchers who need to screen several samples for genetic variants. The objective of this study was to evaluate DNA isolation methods from FFPE tissues
Bing Fang et al.
Biochimie, 95(2), 251-257 (2012-09-27)
siRNA is promising in anti-tumor therapy. The main challenge is lack of tumor-specific intracellular delivery. In this study, a 6 amino acids peptide (A1) with high affinity for vascular endothelial growth factor receptor-1 (VEGFR1) was conjugated with a cell penetrating
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