D8821
Dextrane from Leuconostoc mesenteroides
average mol wt 60,000-76,000
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About This Item
Formule linéaire :
(C6H10O5)n
Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.25
Produits recommandés
Source biologique
bacterial (Leuconostoc mesenteroides)
Niveau de qualité
Forme
powder
Activité optique
[α]20/D 190 to 201 °, c = 2% (w/v) in water
Poids mol.
average mol wt 60,000-76,000
Couleur
white to off-white
Pf
483 °C ((901 °F ))
Solubilité
water: 100 mg/mL at 25 °C, colorless to faintly yellow
Température de stockage
2-8°C
InChI
1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
Clé InChI
FZWBNHMXJMCXLU-UHFFFAOYSA-N
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Description générale
Dextran is an extracellular bacterial polymer of D-glucopyranose. It consists of α-(1→6) linkage in the main chain with a variable amount of α-(1→2), α-(1→3), α-(1→4) branched linkages. Dextran from L. mesenteroides B512F comprises 95% of α- (1→6) linkages and 5% of α-(1→3) branch linkages. Insoluble dextran from L. mesenteroides 1299 contains 63% α-(1→6), 27% of α-(1→2) and 8% of α-(1→3) linkages.
Application
Dextran from Leuconostoc mesenteroides has been used:
- in resuspension of pellets and in Hanks′ balanced salt solution (HBSS) for the isolation of vascular nuclei from frozen post-mortem brain tissue
- to prepare dextran solution in phosphate buffer saline and to maintain corneal hydration and restore corneal thickness to physiological levels of human eyes
- as a polymer solution in the in situ aqueous two-phase systems (ATPS) formation with lysozyme PEGylation reaction
L'utilisation de dextrans comme longs bras hydrophiles améliore les performances des protéines immobilisées qui agissent sur les macromolécules.
Actions biochimiques/physiologiques
Dextran is commercially available as a drug, especially as a blood plasma volume expander. This bacterial polysaccharide has several applications, such as adjuvant, emulsifier, carrier, and stabilizer in the food, pharmaceutical, and chemical industries. Dextran is used in the thickening of jam and ice cream in the food industry. It prevents sugar crystallization and retains moisture. This helps in preserving the flavor and appearance of several food items.
Autres remarques
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 2
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Les clients ont également consulté
Janice M Dias et al.
Experimental eye research, 115, 41-46 (2013-06-27)
Corneal biomechanics is an essential parameter for developing diagnostic and treatment methods of corneal-related diseases. It is widely accepted that corneal mechanical strength stems from the stroma's collagenous composition. However, more comprehensive insight into the mechanical properties within the stroma
Farwa Sarwat et al.
International journal of biological sciences, 4(6), 379-386 (2008-10-28)
On the basis of high enzyme activity a newly isolated strain of L. mesenteroides CMG713 was selected for dextran production. For maximum yield of dextran, effects of various parameters such as pH, temperature, sucrose concentration and incubation period were studied.
Hideto Katsuta et al.
Investigative ophthalmology & visual science, 54(6), 4102-4108 (2013-05-23)
To elucidate the role of signals mediated by EphB4 receptor tyrosine kinase and its transmembrane ephrinB2 ligand in corneal lymphatic capillaries. To detect expression of ephrinB2 and EphB4 in mouse corneas, immunohistochemistry of flat-mount corneas from 6- to 10-week-old wild-type
Zhiyang Li et al.
Journal of biomedical nanotechnology, 9(11), 1945-1949 (2013-09-26)
For reducing the steric hindrance and nonspecific binding of the target DNA, the dextran was used as molecular arms to be immobilized on the surface of magnetic nanoparticles (MNPs). Magnetic separation was used in preparation of dextran-MNPs (DMNPs). Aspartic acid
Elizabeth M Bradshaw et al.
Nature neuroscience, 16(7), 848-850 (2013-05-28)
In our functional dissection of the CD33 Alzheimer's disease susceptibility locus, we found that the rs3865444(C) risk allele was associated with greater cell surface expression of CD33 in the monocytes (t50 = 10.06, P(joint) = 1.3 × 10(-13)) of young
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