A1976

Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonyme(s) : Anti-Aβ 42
• Numéro MDL: MFCD04040171
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: antigen 4 kDa
• Espèces réactives: rat, human, mouse
• Conditionnement: antibody small pack of 25 μg
• Technique(s): dot blot: 0.05-1 μg/mL; immunoblotting: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; indirect ELISA: 1:200; radioimmunoassay: 1:200
• Numéro d'accès UniProt: P05067
• Conditions d'expédition: dry ice
• Température de stockage: −70°C
• Modification post-traductionnelle de la cible: proteolytically cleaved (Ala42)
• Informations sur le gène: human ... APP(351) ; mouse ... App(11820) ; rat ... App(54226)

Description

Description générale

Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients.

Rabbit anti-amyloid peptide β, cleavage site 42 (Aβ42) antibody binds to human, mouse and rat Aβ42.

Immunogène

synthetic peptide of approximately 10 amino acid residues at the C-terminus of Aβ42.

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Rabbit anti-Aβ42 is suitable for use in immunoblot, immunohistochemistry, immunoprecipitation, RIA, ELISA and dot blot applications.

Forme physique

Solution in phosphate buffer, pH 7.4, containing approximately 25 μg of antibody.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves