313M-1

Cytokeratin Cocktail (AE1 & AE3) Mouse Monoclonal Antibody

• NACRES: NA.41
• UNSPSC Code: 12352203
• Conjugate: unconjugated
• Clone: AE1 & AE3, monoclonal
• Application: IHC (p)
• Citations: 4

Propriétés

• biological source: mouse
• Quality Segment: 100, 500
• conjugate: unconjugated
• antibody form: culture supernatant
• antibody product type: primary antibodies
• clone: AE1 & AE3, monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL concentrate (313M-14), vial of 0.5 mL concentrate (313M-15), bottle of 1.0 mL predilute (313M-17), vial of 1.0 mL concentrate (313M-16), bottle of 7.0 mL predilute (313M-18)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• isotype: IgG1κ
• control: breast, colon, prostate, skin
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic
• Gene Information: human ... KRT1(3848)

Description

General description

Anti-cytokeratin cocktail (AE1 & AE3) is a broad-spectrum keratin antibody cocktail. It is composed of mouse monoclonal antibody AE1 that recognizes acidic type I keratins and AE3 that reacts with basic type II keratins. Both clones were generated using epidermal keratin as immunogen. This antibody is useful for identifying cells of epithelial origin and detects most carcinomas of different primarysites. This antibody cocktail can cross-react with other intermediate filaments, such as glialfibrillary acidic protein, giving false-positive staining in glial tumors.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

IVD

IVD

RUO

Other Notes

Cytokeratin Cocktail Positive Control Slides, Product No. 313S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

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Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany