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Y0000510

Desogestrel

European Pharmacopoeia (EP) Reference Standard

Synonyme(s) :

13-Ethyl-11-methylene-18,19-dinor-17α-4-pregnen-20-yn-17-ol

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About This Item

Formule empirique (notation de Hill):
C22H30O
Numéro CAS:
54024-22-5
Poids moléculaire :
310.47
Numéro MDL:
MFCD00869346
Code UNSPSC :
41116107
ID de substance PubChem :
329830993
Nomenclature NACRES :
NA.24

Qualité

pharmaceutical primary standard

Famille d'API

desogestrel

Fabricant/nom de marque

EDQM

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC[C@]12CC(=C)[C@H]3[C@@H](CCC4=CCCC[C@H]34)[C@@H]1CC[C@@]2(O)C#C

InChI

1S/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

Clé InChI

RPLCPCMSCLEKRS-BPIQYHPVSA-N

Informations sur le gène

human ... PGR(5241)

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Description générale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Desogestrel for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Conditionnement

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Autres remarques

Sales restrictions may apply.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Y0000509

Desogestrel, European Pharmacopoeia (EP) Reference Standard

1173268

Desogestrel Related Compound C, United States Pharmacopeia (USP) Reference Standard

1173235

Desogestrel, United States Pharmacopeia (USP) Reference Standard

1173257

Desogestrel Related Compound B, United States Pharmacopeia (USP) Reference Standard

1173246

Desogestrel Related Compound A, United States Pharmacopeia (USP) Reference Standard

1173279

Desogestrel Related Compound D, United States Pharmacopeia (USP) Reference Standard

PHR1830

Desogestrel, Pharmaceutical Secondary Standard; Certified Reference Material

BP816

Desogestrel impurity D, British Pharmacopoeia (BP) Reference Standard

BP817

Desogestrel impurity E, British Pharmacopoeia (BP) Reference Standard

Pictogrammes

Health hazardEnvironment
GHS08,GHS09

Mention d'avertissement

Danger

Mentions de danger

H360FD,H410

Classification des risques

Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

R T Burkman
American journal of obstetrics and gynecology, 168(3 Pt 2), 1033-1040 (1993-03-01)
Desogestrel is a gonane progestogen that in early studies had an improved ratio between desired progestational effects and undesired androgenic effects. A review of more than 50 clinical studies suggests that desogestrel differs from progestins currently used in oral contraception
Giuseppe Benagiano et al.
Annals of the New York Academy of Sciences, 997, 163-173 (2003-12-03)
Progestin-only minipills have been available for over three decades, yet their use has been limited, because of a documented lower efficacy when compared to pills that combine estrogen and progestin. The availability of a new low-dose progestin-only minipill containing 75
D F Archer
American journal of obstetrics and gynecology, 170(5 Pt 2), 1550-1555 (1994-05-01)
Desogestrel is a highly selective gonane progestin. A monophasic formulation containing 150 micrograms of desogestrel and 30 micrograms of ethinyl estradiol has recently been approved as an oral contraceptive (OC) in the United States. Although desogestrel-containing formulations are new to
P G Stubblefield
American journal of obstetrics and gynecology, 168(3 Pt 2), 1047-1052 (1993-03-01)
Epidemiologic research has shown that current low-dose estrogen oral contraceptives are associated with a low risk of vascular events (e.g., myocardial infarction, stroke, and venous thrombosis or thromboembolism). Yet questions still persist about the effects of low-dose oral contraceptives on
K Fotherby
Contraception, 51(1), 3-12 (1995-01-01)
The clinical experience with a combined oral contraceptive (COC) containing 150 micrograms desogestrel and 30 micrograms ethinylestradiol is reviewed. Fourteen clinical trials have been reported involving over 44,000 women for more than 190,000 cycles. None of the 17 pregnancies which
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