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PHR1452

Supelco

Carprofen

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

Carprofen, CAR, 6-Chloro-α-methyl-9H-carbazole-2-acetic acid

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About This Item

Formule empirique (notation de Hill):
C15H12ClNO2
Numéro CAS:
Poids moléculaire :
273.71
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to Ph. Eur. Y0000846
traceable to USP 1096699

Famille d'API

carprofen

CofA (certificat d'analyse)

current certificate can be downloaded

Conditionnement

pkg of 1 g

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-8°C

Chaîne SMILES 

CC(C(O)=O)c1ccc2c(c1)[nH]c3ccc(Cl)cc23

InChI

1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)

Clé InChI

PUXBGTOOZJQSKH-UHFFFAOYSA-N

Informations sur le gène

human ... PTGS2(5743)

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Description générale

Carprofen is a nonsteroidal anti-inflammatory drug (NSAID), majorly used as equine medicine. It is known to be commonly present in the environment as a contaminant.
Pharmaceutical secondary standard for application in quality control. Provides pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Carprofen has been used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA3000 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Conseils de prudence

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Consulter la Bibliothèque de documents

Capillary electrophoresis for the analysis of non-steroidal anti-inflammatory drugs
Macia A, et al.
TrAC, Trends in Analytical Chemistry, 26(2), 133-153 (2007)
A novel two-dimensional liquid chromatographic system for the online toxicity prediction of pharmaceuticals and related substances
Li L, et al.
Journal of Hazardous Materials, 293, 15-20 (2015)
Nonsteroidal anti-inflammatory drug metabolism studies in horses in view of doping control: analytical strategies and challenges
Waraksa E, et al.
TrAC, Trends in Analytical Chemistry, 11(30), 3767-3792 (2019)
Alessandro Silvani et al.
PloS one, 9(6), e100536-e100536 (2014-06-21)
Cannabinoid type 1 (CB1) receptors are expressed in the nervous and cardiovascular systems. In mice, CB1 receptor deficiency protects from metabolic consequences of a high-fat diet (HFD), increases sympathetic activity to brown fat, and entails sleep anomalies. We investigated whether
Danielle L Freeborn et al.
Toxicology and applied pharmacology, 282(2), 184-194 (2014-12-09)
The electroencephalogram (EEG) is an apical measure, capable of detecting changes in brain neuronal activity produced by internal or external stimuli. We assessed whether pesticides with different modes of action produced different changes in the EEG of adult male Long-Evans

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