PHR1142

Progesterone

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonyme(s) : 4-Pregnene-3,20-dione
• Formule empirique (notation de Hill): C₂₁H₃₀O₂
• Numéro CAS: 57-83-0
• Poids moléculaire : 314.46
• Numéro Beilstein : 1915950
• Numéro CE : 200-350-6
• Numéro MDL: MFCD00003658
• Code UNSPSC : 41116107
• ID de substance PubChem : 329823162
• Nomenclature NACRES : NA.24

Propriétés

• Qualité: certified reference material; pharmaceutical secondary standard
• Niveau de qualité: 300
• Agence: traceable to BP 449; traceable to Ph. Eur. P3300000; traceable to USP 1568007
• Famille d'API: progesterone
• CofA (certificat d'analyse): current certificate can be downloaded
• Technique(s): HPLC: suitable; gas chromatography (GC): suitable
• Pf: 128-132 °C (lit.)
• Application(s): pharmaceutical (small molecule)
• Format: neat
• Température de stockage: 2-30°C
• Chaîne SMILES: CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
• Clé InChI: RJKFOVLPORLFTN-LEKSSAKUSA-N
• Informations sur le gène: human ... PGR(5241)

Description

Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Application

Progesterone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceuticals and environmental samples by liquid chromatography (LC) and gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS), respectively.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Actions biochimiques/physiologiques

Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.

Autres remarques

Steroid hormone produced by the corpus luteum.

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Values of analytes vary lot to lot.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA7142 in the slot below. This is an example certificate only and may not be the lot that you receive.

Informations sur la sécurité

• Pictogrammes: GHS08
• Mention d'avertissement: Danger
• Mentions de danger: H351,H360FD,H362
• Conseils de prudence: P202 - P260 - P263 - P264 - P270 - P308 + P313
• Classification des risques: Carc. 2 - Lact. - Repr. 1A
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3