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PHR1090

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Dopamine hydrochloride

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

2-(3,4-Dihydroxyphényl)éthylamine hydrochloride, 3,4-Dihydroxyphénéthylamine hydrochloride, 3-Hydroxytyramine hydrochloride, 4-(2-Aminoéthyl)-1,2-benzènediol hydrochloride

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About This Item

Formule linéaire :
(HO)2C6H3CH2CH2NH2·HCl
Numéro CAS:
Poids moléculaire :
189.64
Numéro Beilstein :
3656720
Numéro CE :
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material
pharmaceutical secondary standard

Niveau de qualité

Agence

traceable to BP 468
traceable to Ph. Eur. D2690000
traceable to USP 1225204

Famille d'API

dopamine

CofA (certificat d'analyse)

current certificate can be downloaded

Technique(s)

HPLC: suitable
gas chromatography (GC): suitable

Pf

248-250 °C (lit.)

Application(s)

pharmaceutical (small molecule)

Format

neat

Température de stockage

2-30°C

Chaîne SMILES 

Cl[H].NCCc1ccc(O)c(O)c1

InChI

1S/C8H11NO2.ClH/c9-4-3-6-1-2-7(10)8(11)5-6;/h1-2,5,10-11H,3-4,9H2;1H

Clé InChI

CTENFNNZBMHDDG-UHFFFAOYSA-N

Informations sur le gène

human ... ADRB1(153)

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Description générale

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Dopamine is a neurotransmitter which is a naturally occurring catecholamine. Dopamine hydrochloride salt is indicated as a medicine for the treatment of acute congestive and renal failures.

Application

Dopamine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometry, colorimetry and chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Remarque sur l'analyse

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Autres remarques

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Note de bas de page

To see an example of a Certificate of Analysis for this material enter LRAA7131 in the slot below. This is an example certificate only and may not be the lot that you receive.

Produits recommandés

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Pictogrammes

Exclamation mark

Mention d'avertissement

Warning

Mentions de danger

Classification des risques

Skin Sens. 1

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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Certificats d'analyse (COA)

Lot/Batch Number

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Consulter la Bibliothèque de documents

Spectrophotometric methods for the determination of certain catecholamine derivatives in pharmaceutical preparations
Nagaraja P, et al.
Talanta, 46(1), 39-44 (1998)
Rapid Spectrophotometric Determination Of Dopamine Hydrochloride With Chloramine - T
Nagaraja P, et al.
Indian Journal of Pharmaceutical Sciences, 60(2), 99-99 (2016)
Intropin (dopamine hydrochloride) intravenous admixture compatibility
Gardella LA, et al.
American Journal of Hospital Pharmacy, 32(6), 575-578 (1975)
Darae Kang et al.
Poultry science, 100(3), 100964-100964 (2021-03-04)
The effects of early heat conditioning on the acute heat stress response in broilers were investigated via the growth performance, dopamine, serotonin, and corticosterone and the expression of heat shock proteins (HSP) and heat shock factors. One-day-old chicks (n =
Hanneke E M den Ouden et al.
Neuron, 80(4), 1090-1100 (2013-11-26)
Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of these neurotransmitters in probabilistic reversal learning in nearly 700 individuals as a function of two polymorphisms in

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