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49909

Sigma-Aldrich

Lanolin

tested according to Ph. Eur.

Synonyme(s) :

Adeps lanae, Wool fat

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About This Item

Numéro CAS:
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352211
Nomenclature NACRES :
NA.25

Agence

USP/NF
tested according to Ph. Eur.

Niveau de qualité

Température d'inflammation spontanée

833 °F

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Description générale

Lanolin is a wool fat. It is a semisolid of high viscosity. Contact allergy to lanolin (wool alcohols), an important sensitizer, in a central London teaching hospital patch-test population has been reported. Simplified extraction of organochlorine and organophosphorus pesticides, frequently found in lanolin, has been proposed. It is utilized as an emulsifier in pharmaceutical and cosmetic formulations.

Application

Lanolin was used to compose the lanolin ointment to estimate the release kinetics of izotretinon and heparin from various semisolid dosage forms by UV-VIS spectroscopy. It was used to prepare the emulsified aqueous solutions containing crystalline dicarboxylic acid. It may be added as excipient to compose a nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

235.4 °F - closed cup

Point d'éclair (°C)

113 °C - closed cup

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Consulter la Bibliothèque de documents

Flora B de Waard-van der Spek et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 26(7), 598-606 (2015-08-20)
Allergic contact dermatitis (ACD) in children appears to be on the increase, and contact sensitization may already begin in infancy. The diagnosis of contact dermatitis requires a careful evaluation of a patient's clinical history, physical examination, and skin testing. Patch
Wenjian Zhang et al.
Nanotechnology, 25(12), 125101-125101 (2014-02-28)
A novel nanoscale-dispersed eye ointment (NDEO) for the treatment of severe evaporative dry eye has been successfully developed. The excipients used as semisolid lipids were petrolatum and lanolin, as used in conventional eye ointment, which were coupled with medium-chain triglycerides
Oxalic acid as a heterogeneous ice nucleus in the upper troposphere and its indirect aerosol effect.
Zobrist B, et al.
Atmospheric Chemistry and Physics, 6(10), 3115-3129 (2006)
S H Wakelin et al.
The British journal of dermatology, 145(1), 28-31 (2001-07-17)
Lanolin is often stated to be an important sensitizer but some of the available literature is based on the analysis of high-risk patients. To analyse the frequency of contact allergy to lanolin (wool alcohols) in a central London teaching hospital
Cindy-Lee Dennis et al.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 7(6), 473-479 (2012-03-21)
The negative outcomes associated with painful and damaged nipples have been widely documented in the breastfeeding literature. Numerous studies have been conducted evaluating topical preparations to treat nipple pain and damage with equivocal findings. No studies have evaluated the effectiveness

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