8.55115

Aminomethylated polystyrene LL (100-200 mesh)

Novabiochem^®

• Synonyme(s) : AM resin LL (100-200 mesh)
• Code UNSPSC : 13111023
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 200
• Gamme de produits: Novabiochem^®
• Forme: beads
• Capacité de réaction: reaction type: Boc solid-phase peptide synthesis
• Fabricant/nom de marque: Novabiochem^®
• Application(s): peptide synthesis
• Groupe fonctionnel: amine
• Température de stockage: 2-30°C

Description

Description générale

Novabiochem^™′s AM resin is prepared according to optimized protocols by direct aminomethylation of polystyrene ^[1]. This process gives a highly homogeneous and chemically defined support free from potentially reactive chloromethyl groups. This resin can be easily acylated with any appropriate carboxylic acid-containing linker using standard methods of amide bond formation to furnish supports for both Boc and Fmoc batch SPPS and SPOS.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Liaison

Replaces: 01-64-0447

Remarque sur l'analyse

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.30 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
TNBS-Test (positive): passes test
TNBS-Test (after loading with Fmoc-Leu-OH (negative)): passes test
The polymer matrix is copoly (styrene - 1% DVB), 100 - 200 mesh.

Informations légales

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

TMAX is a trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable