345802

Gc-Globulin, Mixed Type, Human Plasma

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

• Synonyme(s) : Gc-Globulin, Mixed Type, Human Plasma
• Numéro CAS: 68476-36-8
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.25

Propriétés

• Source biologique: human plasma
• Niveau de qualité: 100
• Pureté: ≥95% (SDS-PAGE)
• Forme: solid
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Native Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.

Application

Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.

Avertissement

Toxicity: Standard Handling (A)

Forme physique

Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Notes préparatoires

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.

Autres remarques

Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3