1.08121

Bromocresol green

pH indicator, ACS, Reag. Ph Eur

• Synonyme(s) : Bromocresol green, 3,3′,5,5′-Tetrabromo-m-cresolsulfonphthalein, BCG
• Formule empirique (notation de Hill): C₂₁H₁₄Br₄O₅S
• Numéro CAS: 76-60-8
• Poids moléculaire : 698.01
• Numéro MDL: MFCD00005874
• Code UNSPSC : 41116100
• Numéro de classement CE : 200-972-8
• Nomenclature NACRES : NB.21

Propriétés

• product name: Bromocresol green, indicator ACS,Reag. Ph Eur
• Qualité: ACS reagent
• Niveau de qualité: 200
• Agence: reag. Ph. Eur.
• Forme: solid
• Perte: ≤3% loss on drying, 110°C
• visual transition interval: 3.8-5.4, yellow-green to blue
• Pf: 217-218 °C
• Masse volumique apparente: 350 kg/m³
• Température de stockage: no temp limit
• InChI: 1S/C21H14Br4O5S/c1-9-12(7-14(22)19(26)17(9)24)21(13-8-15(23)20(27)18(25)10(13)2)11-5-3-4-6-16(11)31(28,29)30-21/h3-8,26-27H,1-2H3
• Clé InChI: FRPHFZCDPYBUAU-UHFFFAOYSA-N

Description

Application

• Sensitive and selective spectrophotometric assay of piroxicam in pure form, capsule and human blood serum samples via ion-pair complex formation.: This study presents a sensitive spectrophotometric method for determining piroxicam in various forms by forming an ion-pair complex with bromocresol green. This method enhances the accuracy and selectivity of piroxicam assays, providing valuable applications in pharmaceutical analysis and clinical diagnostics (Alizadeh & Keyhanian, 2014).


• A high-throughput colorimetric assay to measure the activity of glutamate decarboxylase.: Bromocresol green is utilized in a high-throughput colorimetric assay to measure the activity of glutamate decarboxylase. This assay is crucial for biochemical studies involving enzyme kinetics and could be applied in drug discovery and metabolic engineering research (Yu et al., 2011).


• Spectrophotometric and HPLC determinations of anti-diabetic drugs, rosiglitazone maleate and metformin hydrochloride, in pure form and in pharmaceutical preparations.: The use of bromocresol green in spectrophotometric and HPLC methods enhances the detection and quantification of anti-diabetic drugs. This research is vital for ensuring the quality and efficacy of pharmaceutical products (Onal, 2009).


• Spectrophotometric determination of lamotrigine in pharmaceutical preparations and urine by charge-transfer complexation.: Bromocresol green is employed in the spectrophotometric determination of lamotrigine, facilitating the analysis of this antiepileptic drug in pharmaceutical and biological samples. This application is essential for therapeutic drug monitoring and pharmaceutical quality control (Alizadeh et al., 2008).

Remarque sur l'analyse

Transition range: pH 3.8 - pH 5.4yellowish green - blue
Appearance of solution: passes test
Loss on drying (110 °C): ≤ 3
Transition range (according to ACS): passes test
Sensitivity test: passes test

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable