07-1389

Anti-phospho-Smad3 (Ser423/425) Antibody

from rabbit

• Synonyme(s) : MAD, mothers against decapentaplegic homolog 3, MAD, mothers against decapentaplegic homolog 3 (Drosophila), Mothers against DPP homolog 3 , SMA- and MAD-related protein 3, SMAD 3 , SMAD family member 3, SMAD, mothers against DPP homolog 3, SMAD, mothers
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: polyclonal
• Species reactivity: mouse, mink
• Application: WB
• Citations: 12

Propriétés

• biological source: rabbit
• Quality Segment: 100
• antibody form: unpurified
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: mouse, mink
• species reactivity (predicted by homology): human, rat
• technique(s): western blot: suitable
• NCBI accession no.: NM_005902
• UniProt accession no.: P84022
• shipped in: wet ice
• target post-translational modification: phosphorylation (pSer423/pSer425)
• Gene Information: human ... SMAD3(4088)

Description

General description

β Three distinct classes of Smads have been defined: the receptor-regulated Smads (R-Smads), which include Smad1, 2, 3, 5 and 8, the common-mediator Smad (co-Smad), Smad4, and the antagonistic or inhibitory Smads (I-Smads), Smad6 and 7. Once in the nucleus, Smads can target a variety of DNA binding proteins to regulate transcriptional responses. ββ

50 kDa

Immunogen

KLH-conjugated, synthetic phospho-peptide corresponding to residues surrounding Ser423/425 of human Smad3.

Épitope : Phosphorylated Ser423/425

Application

&

Domaine de recherche
Signalisation

Biochem/physiol Actions

Detects phosphorylated Smad3 (Ser423 and Ser425).

Physical form

Unpurified rabbit serum in buffer containing 0.05% sodium azide.

Preparation Note

°
dès réception, et avant retrait du bouchon, centrifuger le flacon et mélanger délicatement la solution.

Analysis Note

1:1,000 dilution of this antibody was used to detect Smad3 in UV-treated AKR-2B cell lysate.

Disclaimer

Sauf indication contraire dans notre catalogue ou toute autre documentation associée au(x) produit(s), nos produits sont uniquement destinés à la recherche et ne sauraient être utilisés à d'autres fins, ce qui inclut, sans s'y limiter, les utilisations commerciales non autorisées, les utilisations diagnostiques in vitro, les utilisations thérapeutiques ex vivo ou in vivo, ou tout type de consommation ou d'application chez l'être humain ou chez l'animal.

Informations sur la sécurité

• Classe de stockage: 10 - Combustible liquids
• wgk: WGK 1