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860355C

Avanti

16:0 PC-d62

Avanti Research™ - A Croda Brand 860355C

Synonyme(s) :

1,2-dipalmitoyl-d62-sn-glycero-3-phosphocholine

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About This Item

Formule empirique (notation de Hill):
C40H18NO8PD62
Numéro CAS:
25582-63-2
Poids moléculaire :
796.42
Code UNSPSC :
12352100
Nomenclature NACRES :
NA.12

Pureté

>99% (TLC)

Forme

liquid

Conditionnement

pkg of 1 × 1 mL (860355C-10mg)

Fabricant/nom de marque

Avanti Research™ - A Croda Brand 860355C

Concentration

10 mg/mL (860355C-10mg)

Conditions d'expédition

dry ice

Température de stockage

−20°C

Chaîne SMILES 

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)COC(C([2H])([2H

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1/i1D3,2D3,6D2,7D2,8D2,9D2,10D2,11D2,12D2,13D2,14D2,15D2,16D2,17D2,18D2,19D2,20D2,21D2,22D2,23D2,24D2,25D2,26D2,27D2,28D2,29D2,30D2,31D2,32D2,33D2

Clé InChI

KILNVBDSWZSGLL-PWXLRKPBSA-N

Catégories apparentées

Description générale

16:0 PC-d62 is a deuterated phosphocholine (PC) in which 62 protons of dipalmitoyl are replaced by deuterium.
Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Application

16:0 PC-d62 may be used for the preparation of asymmetric large unilamellar vesicles (aLUVs) for use as cell membrane models.

Conditionnement

5 mL Clear Glass Sealed Ampule (860355C-10mg)

Informations légales

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictogrammes

Skull and crossbonesHealth hazard
GHS06,GHS08

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Organes cibles

Central nervous system, Liver,Kidney

Classe de danger pour l'eau (WGK)

WGK 3

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Preparation of asymmetric phospholipid vesicles for use as cell membrane models
Doktorova M, et al.
Nature Protocols, 13(9), 2086-2101 (2018)
Kalliopi-Kelli A Vandera et al.
Molecular pharmaceutics, 17(7), 2354-2369 (2020-05-01)
Gram-negative bacteria possess numerous defenses against antibiotics, due to the intrinsic permeability barrier of their outer membrane (OM), explaining the recalcitrance of some common and life-threatening infections. We report the formulation of a new drug, PPA148, which shows promising activity
Drew Marquardt et al.
Langmuir : the ACS journal of surfaces and colloids, 33(15), 3731-3741 (2017-01-21)
We measured the transbilayer diffusion of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) in large unilamellar vesicles, in both the gel (Lβ') and fluid (Lα) phases. The choline resonance of headgroup-protiated DPPC exchanged into the outer leaflet of headgroup-deuterated DPPC-d13 vesicles was monitored using 1H
Mitchell DiPasquale et al.
Biochimica et biophysica acta. Biomembranes, 1862(8), 183189-183189 (2020-01-19)
The antioxidant vitamin E is a commonly used vitamin supplement. Although the multi-billion dollar vitamin and nutritional supplement industry encourages the use of vitamin E, there is very little evidence supporting its actual health benefits. Moreover, vitamin E is now
Andrée E Gravel et al.
Biochimica et biophysica acta. Biomembranes, 1862(10), 183379-183379 (2020-06-01)
We present a new membrane mimetic system using a membrane softening detergent commonly known as Tween 80 (TW80), to form oriented systems for solid-state NMR applications. TW80 is a fatty acid ester (oleate) of sorbitan polyethoxylate and a mild non-ionic
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Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in the equilibrium: nM1<=>Mn

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