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Key Documents

SML1553

Sigma-Aldrich

MS049 hydrochloride

≥98% (HPLC)

Synonyme(s) :

N-Methyl-4-(phenylmethoxy)-1-piperidineethanamine hydrochloride

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About This Item

Formule empirique (notation de Hill):
C15H24N2O · xHCl
Numéro CAS:
Poids moléculaire :
248.36 (free base basis)
Code UNSPSC :
12352200
ID de substance PubChem :
Nomenclature NACRES :
NA.77

Niveau de qualité

Pureté

≥98% (HPLC)

Forme

powder

Couleur

white to beige

Solubilité

H2O: 20 mg/mL, clear

Température de stockage

2-8°C

Chaîne SMILES 

CNCCN(CC1)CCC1OCC2=CC=CC=C2.[H]Cl

InChI

1S/C15H24N2O.ClH/c1-16-9-12-17-10-7-15(8-11-17)18-13-14-5-3-2-4-6-14;/h2-6,15-16H,7-13H2,1H3;1H

Clé InChI

FJZNVFFTIKWXMA-UHFFFAOYSA-N

Actions biochimiques/physiologiques

MS049 is a potent and selective inhibitor of protein arginine methyltransferases (PRMTs) PRMT 4 and PRMT6. MS049 is active in cells. For full characterization details, please visit the MS049 probe summary on the Structural Genomics Consortium (SGC) website.

MS049N is the negative control for the active probe, MS049. To request a sample of the negative control from the SGC, click here.

To learn about other SGC chemical probes for epigenetic targets, visit sigma.com/sgc

Caractéristiques et avantages

MS049 is an epigenetic chemical probe available through a partnership with the Structural Genomics Consortium (SGC). To learn more and view other SGC epigenetic probes, visit sigma.com/SGC.
This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 3 Oral

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

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Articles

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We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

We offer a variety of small molecule research tools, such as transcription factor modulators, inhibitors of chromatin modifying enzymes, and agonists/antagonists for target identification and validation in gene regulation research; a selection of these research tools is shown below.

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