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Key Documents

P2172

Sigma-Aldrich

C-Phycocyanin from Spirulina sp.

lyophilized powder

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About This Item

Numéro CAS:
11016-15-2
Numéro MDL:
MFCD00130691
Code UNSPSC :
12352202
Nomenclature NACRES :
NA.56

Source biologique

Spirulina

Niveau de qualité

200

Forme

lyophilized powder

Composition

Protein, ~40% Lowry

Concentration

30-50% protein (Lowry)

Température de stockage

2-8°C

Informations sur le gène

Spirulina ... cpcA(41380954) , cpcB(41380955)

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Description générale

C-Phycocyanin is a protein pigment, that is soluble in water. It is an important constituent of Spirulina platensis.

Application

C-Phycocyanin from Spirulina sp. has been used:
  • as a standard to characterize the fluorescence interactions and oxidation behaviors for model compounds
  • as a standard to confirm the antibacterial activity
  • to characterize the recombinantly expressed α-subunit of C-phycocyanin from Synechocystis sp. PCC6803 (HisCPC)
  • to identify the phycocyanin from water extracted Spirulina maxima sample

Actions biochimiques/physiologiques

C-phycocyanin, a biliprotein with antioxidant properties, was shown to induce apoptosis in HeLa cells by stimulating expression of pro-apoptotic genes as well as by inducing increased release of cytochrome c from the mitochondria.
C-phycocyanin can act as an active inhibitor of A53Tα-synuclein. It possess anti-inflammatory properties.

Conditionnement

Package size based on protein content

Forme physique

Partially purified, contains sucrose, dithioerythritol and sodium azide as preservatives

Pictogrammes

Skull and crossbonesEnvironment
GHS06,GHS09

Mention d'avertissement

Danger

Mentions de danger

H302 + H332,H311,H411

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

C-phycocyanin: a potent peroxyl radical scavenger in vivo and in vitro
Bhat VB and Madyastha KM
Biochemical and biophysical research communications, 275(1), 20-25 (2000)
C-Phycocyanin from Spirulina Inhibits ?-Synuclein and Amyloid ?-Fibril Formation but Not Amorphous Aggregation
Liu Y, et al.
Journal of Natural Products, 82(1), 66-73 (2019)
Jun-Ichi Ishihara et al.
Biochemistry and biophysics reports, 34, 101469-101469 (2023-05-01)
The one-dimensional multicellular cyanobacterium, Anabaena sp. PCC 7120, exhibits a simple topology consisting of two types of cells under the nitrogen-depleted conditions. Although the differentiated (heterocyst) and undifferentiated cells (vegetative cells) were distinguished by their cellular shapes, we found that
Bing Li et al.
Biotechnology and applied biochemistry, 43(Pt 3), 155-164 (2005-12-01)
C-phycocyanin (C-PC), a water-soluble protein pigment, isolated from Spirulina platensis, is of great importance because of its various medical and pharmacological properties. In the present study, we first investigated the effect of highly purified C-PC on growth and proliferation of
Screening of anti-bacterial activity of C-phycocyanin and its minimum inhibitory concentration (MIC) determination by agar dilution method
Murugan T and Madhavan R
Asian Journal of Biological Sciences, 6(1), 41-45 (2011)
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