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M6145

Sigma-Aldrich

1-Thioglycérol

liquid, BioReagent, suitable for cell culture, ≥97% (titration)

Synonyme(s) :

α-Monothioglycérol, α-Thioglycérol, 3-Mercapto-1,2-propanediol

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About This Item

Formule linéaire :
HSCH2CH(OH)CH2OH
Numéro CAS:
Poids moléculaire :
108.16
Beilstein:
1732046
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352211
ID de substance PubChem :
Nomenclature NACRES :
NA.75
Le tarif et la disponibilité ne sont pas disponibles actuellement.

Source biologique

synthetic (organic)

Niveau de qualité

Gamme de produits

BioReagent

Essai

≥97% (titration)

Forme

liquid

Technique(s)

cell culture | mammalian: suitable
single cell analysis: suitable

Indice de réfraction

n20/D 1.527 (lit.)

pb

118 °C/5 mmHg (lit.)

Solubilité

water: miscible 0.1 M

Densité

1.25 g/mL at 25 °C (lit.)

Température de stockage

2-8°C

Chaîne SMILES 

OCC(O)CS

InChI

1S/C3H8O2S/c4-1-3(5)2-6/h3-6H,1-2H2

Clé InChI

PJUIMOJAAPLTRJ-UHFFFAOYSA-N

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Cet article
M2172108704M1753
1-Thioglycérol liquid, BioReagent, suitable for cell culture, ≥97% (titration)

M6145

1-Thioglycérol

1-Thioglycérol BioXtra, ≥97%

M2172

1-Thioglycérol

1-Thioglycérol EMPROVE® ESSENTIAL, NF

108704

1-Thioglycérol

1-Thioglycérol ≥97%

M1753

1-Thioglycérol

assay

≥97% (titration)

assay

≥97%

assay

-

assay

≥97%

technique(s)

cell culture | mammalian: suitable, single cell analysis: suitable

technique(s)

-

technique(s)

-

technique(s)

-

solubility

water: miscible 0.1 M

solubility

-

solubility

-

solubility

-

Quality Level

200

Quality Level

200

Quality Level

500

Quality Level

200

form

liquid

form

liquid

form

liquid

form

liquid

Application

Le 1-thioglycérol a été utilisé comme constituant d′un milieu de culture afin de stimuler la prolifération dans des études de culture cellulaire portant sur des neurones corticaux et hippocampiques embryonnaires, des lignées de mastocytes de moelle osseuse de souris et des lignées de cellules Β humaines.

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

Skull and crossbones

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Skin Irrit. 2 - Skin Sens. 1B

Code de la classe de stockage

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

210.2 °F - closed cup

Point d'éclair (°C)

99 °C - closed cup

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Certificats d'analyse (COA)

Lot/Batch Number

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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Suji Lee et al.
Stem cells (Dayton, Ohio), 36(10), 1552-1566 (2018-07-14)
Although autologous induced pluripotent stem cells (iPSCs) can potentially be useful for treating patients without immune rejection, in reality it will be extremely expensive and labor-intensive to make iPSCs to realize personalized medicine. An alternative approach is to make use
L Tang et al.
Journal of biomedical materials research, 41(2), 333-340 (1998-06-25)
Biomaterial-mediated complement activation repeatedly has been invoked as a trigger of phagocyte reactions and inflammation. However, a direct correlation between complement activation and inflammatory responses to biomaterial surfaces has yet to be established. Using an animal implantation model and gold
Morgan Oatley et al.
Nature communications, 11(1), 586-586 (2020-01-31)
The endothelial to haematopoietic transition (EHT) is the process whereby haemogenic endothelium differentiates into haematopoietic stem and progenitor cells (HSPCs). The intermediary steps of this process are unclear, in particular the identity of endothelial cells that give rise to HSPCs
Valérie Gagnard et al.
Bioorganic & medicinal chemistry, 12(6), 1393-1402 (2004-03-17)
A new enzyme-labile group called S-acyl-3-thiopropyl group (SATP) has been synthesized from allylic esters of phosphonate. After demonstration of the enzyme-labile character of the SATP in cellular extracts, it has been introduced onto the phosphonate moiety of PFA (Foscarnet) to
P Tengvall et al.
Biomaterials, 17(10), 1001-1007 (1996-05-01)
Thiol-modified surfaces are chemically well defined and suited for surface biological model experiments and biomaterials research. 3-Mercapto-1,2-propanediol (mercaptoglycerol, MG), immobilized on gold, spontaneously binds immunoglobulins from human serum and activates the complement system. The surface-bound complement factors were detected by

Questions

1–4 of 4 Questions  
  1. How long is degradation time of Monothioglycerol (MTG)? In other words, how long can I save it in the refrigerator?

    1 answer
    1. This product is not assigned an expiration date. It is assigned a recommended retest date of 5 years after the quality release date. It will be stable at 2 - 8 °C during this period if not contaminated and securely closed.

      A recommended retest date is the period during which the product is expected to remain within established stability specifications, provided that it has been stored under defined conditions. After the Retest Date, product samples should be examined to ensure that the product is still in compliance with the established specifications.
      For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/US/en/life-science/quality-and-regulatory-management/quality-services.

      Helpful?

  2. What is the concentration of the 1-thioglycerol?

    1 answer
    1. The liquid is not a solution of 1-thioglycerol in some solvent. Rather, it is a neat liquid (i.e., essentially pure 1-thioglycerol). Based on a density of 1.245 g/mL and a molecular weight of 108.2 g/mole, one can calculate an effective molarity of 11.5 M. This information may be found on the M1753 product information sheet.

      Helpful?

  3. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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