Accéder au contenu
Merck

Passer à

H7250

Histamine dihydrochloride

≥99% (TLC), powder, endogenous histamine receptor agonist

Synonyme(s) :

2-(4-Imidazolyl)ethylamine dihydrochloride

Se connecter pour consulter les tarifs organisationnels et contractuels.

Sélectionner une taille de conditionnement

Changer de vue
À vous/RéférenceDisponibilitéPrix

A propos de cet article

Formule empirique (notation de Hill) :
C5H9N3 · 2HCl
Numéro CAS:
Poids moléculaire :
184.07
NACRES:
NA.77
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352116
EC Number:
200-298-4
MDL number:
Beilstein/REAXYS Number:
3624116
Assay:
≥99% (TLC)
Form:
powder
Le tarif et la disponibilité ne sont pas disponibles actuellement.
Service technique
Besoin d'aide ? Notre équipe de scientifiques expérimentés est là pour vous.
Laissez-nous vous aider


Nom du produit

Histamine dihydrochloride, ≥99% (TLC), powder

Quality Segment

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

249-252 °C (lit.)

storage temp.

2-8°C

SMILES string

Cl[H].Cl[H].NCCc1c[nH]cn1

InChI

1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H

InChI key

PPZMYIBUHIPZOS-UHFFFAOYSA-N

Gene Information

General description

Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.

Application

Histamine dihydrochloride has been used:
  • as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
  • to determine its level in fish using HPLC (high performance liquid chromatography)
  • to assess the tracheal response to antigens in guinea-pigs

Biochem/physiol Actions

Endogenous H1 and H2 histamine receptor agonist; activates nitric oxide synthetase; potent vasodilator.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Comparer avec des articles similaires

Voir la comparaison complète

Montrer les différences

1 of 1

Cet article
53300H06000001309009
form

powder

form

powder or crystals

form

-

form

-

assay

≥99% (TLC)

assay

≥99.0% (AT)

assay

-

assay

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C

color

white to off-white

color

-

color

-

color

-

Gene Information

human ... HRH1(3269), HRH2(3274)

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)


Still not finding the right product?

Explore all of our products under Histamine dihydrochloride


pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Classe de stockage

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



Faites votre choix parmi les versions les plus récentes :

Certificats d'analyse (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

Si vous avez besoin d'assistance, veuillez contacter Service Clients

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents



Questions

1–6 of 6 Questions  
  1. Is Histamine dihydrochloride H7250 traceable to SI units?

    1 answer
    1. This product is sold by weight. It is a powder that is at least 99% pure. There is no unit value associated with this material. The 'SI' term tends to refer to serum levels as nmol/L.

      To discuss further, please navigate to the link https://www.sigmaaldrich.com/techservice, click on "Product Technical Inquiries" under the Products Section with all the required information so that a member of the Technical Service team can reach out to assist further. Thank you.

      Helpful?

  2. How should Product H7250, Histamine dihydrochloride, be stored?

    1 answer
    1. This product is a powder and should be stored at 2-8°C, dessicated.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. How should Product H7250, Histamine dihydrochloride, be dissolved?

    1 answer
    1. We test the solubility of this product in water at a concentration of 50 mg/mL. This yields a clear, colorless to faint yellow solution.

      Helpful?

  5. How does the storage temperature relate to shipping conditions?

    1 answer
    1. The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment.

      Helpful?

  6. What is the solution stablity of Product H7250, Histamine dihydrochloride?

    1 answer
    1. Solutions can be stored at 2-4°C for 8 weeks, and at -20°C for up to 12 months. Once thawed, solutions should be used within 6 hours or discarded. Solutions are light sensitive and need to be protected from light.

      Helpful?

Reviews

No rating value

Active Filters